| Reaction Details |
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 | Report a problem with these data |
| Target | Mas-related G-protein coupled receptor member X1 |
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| Ligand | BDBM50413336 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_562318 (CHEMBL1015292) |
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| EC50 | 316.23±n/a nM |
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| Citation |  Malik, L; Kelly, NM; Ma, JN; Currier, EA; Burstein, ES; Olsson, R Discovery of non-peptidergic MrgX1 and MrgX2 receptor agonists and exploration of an initial SAR using solid-phase synthesis. Bioorg Med Chem Lett19:1729-32 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mas-related G-protein coupled receptor member X1 |
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| Name: | Mas-related G-protein coupled receptor member X1 |
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| Synonyms: | MRGPRX1 | MRGX1 | MRGX1_HUMAN | SNSR3 | SNSR4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36253.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_516621 |
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| Residue: | 322 |
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| Sequence: | MDPTISTLDTELTPINGTEETLCYKQTLSLTVLTCIVSLVGLTGNAVVLWLLGCRMRRNA
FSIYILNLAAADFLFLSGRLIYSLLSFISIPHTISKILYPVMMFSYFAGLSFLSAVSTER
CLSVLWPIWYRCHRPTHLSAVVCVLLWALSLLRSILEWMLCGFLFSGADSAWCQTSDFIT
VAWLIFLCVVLCGSSLVLLIRILCGSRKIPLTRLYVTILLTVLVFLLCGLPFGIQFFLFL
WIHVDREVLFCHVHLVSIFLSALNSSANPIIYFFVGSFRQRQNRQNLKLVLQRALQDASE
VDEGGGQLPEEILELSGSRLEQ
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| BDBM50413336 |
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| n/a |
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| Name | BDBM50413336 |
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| Synonyms: | CHEMBL503202 |
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| Type | Small organic molecule |
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| Emp. Form. | C34H35F3N6O3 |
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| Mol. Mass. | 632.6753 |
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| SMILES | CC[C@@H](C)[C@@H]1C(=O)Nc2ccc(cc2-c2nc3cc(ccc3n12)C(=O)NCc1cccc(c1)C(F)(F)F)N1CC[C@@H](C1)NC(C)=O |r,@:33| |
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| Structure | 
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