| Reaction Details |
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 | Report a problem with these data |
| Target | Mas-related G-protein coupled receptor member X2 |
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| Ligand | BDBM50413340 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_562320 (CHEMBL1015294) |
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| EC50 | 501±n/a nM |
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| Citation |  Malik, L; Kelly, NM; Ma, JN; Currier, EA; Burstein, ES; Olsson, R Discovery of non-peptidergic MrgX1 and MrgX2 receptor agonists and exploration of an initial SAR using solid-phase synthesis. Bioorg Med Chem Lett19:1729-32 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mas-related G-protein coupled receptor member X2 |
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| Name: | Mas-related G-protein coupled receptor member X2 |
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| Synonyms: | MRGPRX2 | MRGX2 | MRGX2_HUMAN | Mas-related G protein-coupled receptor X2 (MRGPRX2) | Mas-related G-protein coupled receptor member X2 |
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| Type: | GPCR |
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| Mol. Mass.: | 37104.79 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q96LB1 |
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| Residue: | 330 |
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| Sequence: | MDPTTPAWGTESTTVNGNDQALLLLCGKETLIPVFLILFIALVGLVGNGFVLWLLGFRMR
RNAFSVYVLSLAGADFLFLCFQIINCLVYLSNFFCSISINFPSFFTTVMTCAYLAGLSML
STVSTERCLSVLWPIWYRCRRPRHLSAVVCVLLWALSLLLSILEGKFCGFLFSDGDSGWC
QTFDFITAAWLIFLFMVLCGSSLALLVRILCGSRGLPLTRLYLTILLTVLVFLLCGLPFG
IQWFLILWIWKDSDVLFCHIHPVSVVLSSLNSSANPIIYFFVGSFRKQWRLQQPILKLAL
QRALQDIAEVDHSEGCFRQGTPEMSRSSLV
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| BDBM50413340 |
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| n/a |
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| Name | BDBM50413340 |
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| Synonyms: | CHEMBL505715 |
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| Type | Small organic molecule |
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| Emp. Form. | C81H113N19O19S2 |
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| Mol. Mass. | 1721.01 |
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| SMILES | C[C@@H](O)[C@@H]1NC(=O)[C@@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc2ccccc2)NC1=O)C(=O)N[C@@H](CCCCN)C(O)=O)NC(=O)[C@@H]1CCCN1 |r| |
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| Structure | 
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