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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | C-X-C chemokine receptor type 3 | ||
| Ligand | BDBM50413608 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_497564 (CHEMBL998621) | ||
| Ki | 158.49±n/a nM | ||
| Citation |  Wijtmans, M; Verzijl, D; van Dam, CM; Bosch, L; Smit, MJ; Leurs, R; de Esch, IJ Exploring a pocket for polycycloaliphatic groups in the CXCR3 receptor with the aid of a modular synthetic strategy. Bioorg Med Chem Lett19:2252-7 (2009) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| C-X-C chemokine receptor type 3 | |||
| Name: | C-X-C chemokine receptor type 3 | ||
| Synonyms: | AAO92295.1 | C-X-C chemokine receptor type 3 | C-X-C chemokine receptor type 3 (CXCR3) | C-X-C chemokine receptor type 3 (CXCR3A) | CXCR3 | CXCR3A | CXCR3_HUMAN | GPR9 | chemokine (C-X-C motif) receptor 3 | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 40665.65 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | n/a | ||
| Residue: | 368 | ||
| Sequence: |
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| BDBM50413608 | |||
| n/a | |||
| Name | BDBM50413608 | ||
| Synonyms: | CHEMBL470002 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H30ClFN2 | ||
| Mol. Mass. | 376.938 | ||
| SMILES | Fc1cc(Cl)ccc1CN1CCC(CC1)NC1C2CC3CC(C2)CC1C3 |TLB:22:21:25:18.17.16,22:17:20.21.23:25,THB:16:17:20:23.24.25,16:24:20:18.22.17,15:16:20.21.23:25,(19.96,-46.51,;21.3,-45.74,;22.63,-46.51,;23.97,-45.74,;25.3,-46.51,;23.96,-44.2,;22.63,-43.43,;21.31,-44.2,;19.98,-43.43,;18.64,-44.2,;17.3,-43.42,;15.97,-44.2,;15.97,-45.75,;17.3,-46.52,;18.64,-45.75,;14.63,-46.52,;13.32,-45.7,;11.93,-46.32,;11.03,-45.19,;10.93,-43.78,;9.27,-43.22,;10.27,-44.41,;10.34,-45.93,;11.72,-43.75,;13.27,-44.19,;12.28,-43.16,)| | ||
| Structure | 
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