| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin K |
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| Ligand | BDBM31970 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_581588 (CHEMBL1062475) |
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| IC50 | 3162.28±n/a nM |
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| Citation |  Bethel, PA; Gerhardt, S; Jones, EV; Kenny, PW; Karoutchi, GI; Morley, AD; Oldham, K; Rankine, N; Augustin, M; Krapp, S; Simader, H; Steinbacher, S Design of selective Cathepsin inhibitors. Bioorg Med Chem Lett19:4622-5 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cathepsin K |
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| Name: | Cathepsin K |
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| Synonyms: | CATK_HUMAN | CTSK | CTSO | CTSO2 | Cathepsin O | Cathepsin O2 | Cathepsin X |
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| Type: | Enzyme |
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| Mol. Mass.: | 36975.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P43235 |
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| Residue: | 329 |
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| Sequence: | MWGLKVLLLPVVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIH
NLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVD
YRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGG
YMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVA
RVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGE
NWGNKGYILMARNKNNACGIANLASFPKM
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| BDBM31970 |
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| n/a |
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| Name | BDBM31970 |
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| Synonyms: | Dipeptidyl nitrile inhibitor, 1 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H16ClN3O2 |
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| Mol. Mass. | 341.792 |
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| SMILES | Clc1cccc(C[C@H](NC(=O)c2ccccc2)C(=O)NCC#N)c1 |r| |
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| Structure | 
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