Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Neuropeptide Y receptor type 5 | ||
| Ligand | BDBM50417036 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_664979 (CHEMBL1259936) | ||
| Ki | 0.0631±n/a nM | ||
| Citation |  Leslie, CP; Bentley, J; Biagetti, M; Contini, S; Di Fabio, R; Donati, D; Genski, T; Guery, S; Mazzali, A; Merlo, G; Pizzi, DA; Sacco, F; Seri, C; Tessari, M; Zonzini, L; Caberlotto, L Discovery and structure-activity relationship of a novel spirocarbamate series of NPY Y5 antagonists. Bioorg Med Chem Lett20:6103-7 (2010) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Neuropeptide Y receptor type 5 | |||
| Name: | Neuropeptide Y receptor type 5 | ||
| Synonyms: | NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 50746.64 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q15761 | ||
| Residue: | 445 | ||
| Sequence: |
| ||
| BDBM50417036 | |||
| n/a | |||
| Name | BDBM50417036 | ||
| Synonyms: | CHEMBL1257992 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C24H24FN5O2 | ||
| Mol. Mass. | 433.4781 | ||
| SMILES | Fc1ccccc1-c1ccc(NC[C@H]2CC[C@@]3(CN(C(=O)O3)c3ccccn3)CC2)nn1 |r,wU:13.13,wD:16.22,(-7.93,-14.34,;-8.69,-13,;-10.22,-12.98,;-10.98,-11.63,;-10.19,-10.31,;-8.65,-10.33,;-7.9,-11.68,;-6.36,-11.69,;-5.6,-13.04,;-4.07,-13.06,;-3.28,-11.75,;-1.74,-11.77,;-1,-13.12,;.54,-13.14,;1.34,-11.82,;2.88,-11.84,;3.62,-13.19,;4.75,-12.16,;6.09,-12.93,;5.77,-14.44,;6.8,-15.58,;4.24,-14.6,;7.5,-12.31,;8.74,-13.22,;10.15,-12.59,;10.31,-11.06,;9.06,-10.15,;7.66,-10.78,;2.82,-14.51,;1.29,-14.48,;-4.03,-10.4,;-5.57,-10.37,)| | ||
| Structure | 
| ||