| Reaction Details |
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 | Report a problem with these data |
| Target | Vasopressin V1b receptor |
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| Ligand | BDBM50418397 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_746774 (CHEMBL1776943) |
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| Ki | 1258.93±n/a nM |
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| Citation |  Napier, S; Wishart, G; Arbuckle, W; Baker, J; Barn, D; Bingham, M; Brown, A; Byford, A; Claxton, C; Craighead, M; Buchanan, K; Fielding, L; Gibson, L; Goodwin, R; Goutcher, S; Irving, N; MacSweeney, C; Milne, R; Mort, C; Presland, J; Sloan, H; Thomson, F; Turnbull, Z; Young, T The discovery of novel 8-azabicyclo[3.2.1]octan-3-yl)-3-(4-chlorophenyl) propanamides as vasopressin V1A receptor antagonists. Bioorg Med Chem Lett21:3163-7 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Vasopressin V1b receptor |
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| Name: | Vasopressin V1b receptor |
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| Synonyms: | AVPR V1b | AVPR V3 | AVPR1B | AVPR3 | Antidiuretic hormone receptor 1b | V1BR_HUMAN | V1bR | VASOPRESSIN V1B | VPR3 | Vasopressin V1b receptor | Vasopressin V1b receptor (V1b) | Vasopressin V3 | Vasopressin V3 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 46985.01 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P47901 |
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| Residue: | 424 |
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| Sequence: | MDSGPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVLVLATGGNLAVLLTLG
QLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMFA
STYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVIQG
SGVLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKTQAWRVG
GGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAPFFSV
QMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPLRHLACCGGPQ
PRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSGRPRPEESPRDLELADGEGTAE
TIIF
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| BDBM50418397 |
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| n/a |
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| Name | BDBM50418397 |
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| Synonyms: | CHEMBL1773857 |
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| Type | Small organic molecule |
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| Emp. Form. | C34H45ClN4O4S |
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| Mol. Mass. | 641.264 |
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| SMILES | COc1cc(C)c(c(C)c1C)S(=O)(=O)N[C@@H](Cc1ccc(Cl)cc1)C(=O)N(CCCN1CCN(C)CC1)Cc1ccccc1 |r| |
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| Structure | 
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