| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM50418835 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_756114 (CHEMBL1804370) |
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| EC50 | 7.9±n/a nM |
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| Citation |  Stocks, MJ; Alcaraz, L; Bailey, A; Bonnert, R; Cadogan, E; Christie, J; Connolly, S; Cook, A; Fisher, A; Flaherty, A; Hill, S; Humphries, A; Ingall, A; Jordan, S; Lawson, M; Mullen, A; Nicholls, D; Paine, S; Pairaudeau, G; St-Gallay, S; Young, A Design driven HtL: The discovery and synthesis of new high efficacyß2-agonists. Bioorg Med Chem Lett21:4027-31 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor |
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| Type: | n/a |
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| Mol. Mass.: | 46461.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07550 |
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| Residue: | 413 |
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| Sequence: | MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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| BDBM50418835 |
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| n/a |
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| Name | BDBM50418835 |
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| Synonyms: | CHEMBL1800474 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H31N3O4S |
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| Mol. Mass. | 457.586 |
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| SMILES | CC(C)(CNCCc1ccc(O)c2[nH]c(=O)sc12)NC(=O)CCOCCc1ccccc1 |
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| Structure | 
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