| Reaction Details |
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 | Report a problem with these data |
| Target | Casein kinase II subunit alpha' |
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| Ligand | BDBM50420558 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_841711 (CHEMBL2092254) |
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| IC50 | 8200±n/a nM |
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| Citation |  Hou, Z; Nakanishi, I; Kinoshita, T; Takei, Y; Yasue, M; Misu, R; Suzuki, Y; Nakamura, S; Kure, T; Ohno, H; Murata, K; Kitaura, K; Hirasawa, A; Tsujimoto, G; Oishi, S; Fujii, N Structure-based design of novel potent protein kinase CK2 (CK2) inhibitors with phenyl-azole scaffolds. J Med Chem55:2899-903 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Casein kinase II subunit alpha' |
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| Name: | Casein kinase II subunit alpha' |
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| Synonyms: | CK2A2 | CSK22_HUMAN | CSNK2A2 | Casein kinase II alpha (prime) | Casein kinase II alpha' | Casein kinase II subunit alpha (CK2A2) | Casein kinase II subunit alpha (CSNK2A2) |
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| Type: | Protein |
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| Mol. Mass.: | 41223.82 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 350 |
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| Sequence: | MPGPAAGSRARVYAEVNSLRSREYWDYEAHVPSWGNQDDYQLVRKLGRGKYSEVFEAINI
TNNERVVVKILKPVKKKKIKREVKILENLRGGTNIIKLIDTVKDPVSKTPALVFEYINNT
DFKQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLA
EFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNY
DQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALD
LLDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQSQPCADNAVLSSGLTAAR
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| BDBM50420558 |
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| n/a |
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| Name | BDBM50420558 |
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| Synonyms: | CHEMBL2087018 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H13N3O4S |
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| Mol. Mass. | 307.325 |
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| SMILES | CC(C)OC(=O)Nc1nnc(s1)-c1ccc(cc1)C(O)=O |
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| Structure | 
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