| Reaction Details |
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 | Report a problem with these data |
| Target | Glucose-dependent insulinotropic receptor |
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| Ligand | BDBM50424575 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_933672 (CHEMBL2320533) |
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| Ki | 7.0±n/a nM |
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| Citation |  Darout, E; Robinson, RP; McClure, KF; Corbett, M; Li, B; Shavnya, A; Andrews, MP; Jones, CS; Li, Q; Minich, ML; Mascitti, V; Guimarães, CR; Munchhof, MJ; Bahnck, KB; Cai, C; Price, DA; Liras, S; Bonin, PD; Cornelius, P; Wang, R; Bagdasarian, V; Sobota, CP; Hornby, S; Masterson, VM; Joseph, RM; Kalgutkar, AS; Chen, Y Design and synthesis of diazatricyclodecane agonists of the G-protein-coupled receptor 119. J Med Chem56:301-19 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glucose-dependent insulinotropic receptor |
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| Name: | Glucose-dependent insulinotropic receptor |
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| Synonyms: | G-protein coupled receptor 119 (GPR119) | GP119_HUMAN | GPR119 | Glucose-dependent insulinotropic receptor |
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| Type: | Protein |
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| Mol. Mass.: | 36901.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q8TDV5 |
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| Residue: | 335 |
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| Sequence: | MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISG
LLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLKIMSGF
VAGACIAGLWLVSYLIGFLPLGIPMFQQTAYKGQCSFFAVFHPHFVLTLSCVGFFPAMLL
FVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFKALRTVSVLIGSFALSWTP
FLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKV
LTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
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| BDBM50424575 |
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| n/a |
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| Name | BDBM50424575 |
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| Synonyms: | CHEMBL2312159 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H29FN8O3 |
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| Mol. Mass. | 508.548 |
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| SMILES | Cc1c(Oc2ccc(cc2F)-n2cnnn2)ncnc1N1C2CC3CC1CC(C2)N3C(=O)OC(C)(C)C |TLB:28:27:24:22.21.20,20:21:29:26.25.24,20:25:29:22.28.21,19:20:29.27.26:24,THB:28:21:29.27.26:24,30:29:24:22.21.20| |
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| Structure | 
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