| Reaction Details |
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 | Report a problem with these data |
| Target | Low molecular weight phosphotyrosine protein phosphatase |
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| Ligand | BDBM50425808 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_937593 (CHEMBL2321062) |
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| IC50 | 2900±n/a nM |
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| Citation |  He, Y; Xu, J; Yu, ZH; Gunawan, AM; Wu, L; Wang, L; Zhang, ZY Discovery and evaluation of novel inhibitors of mycobacterium protein tyrosine phosphatase B from the 6-Hydroxy-benzofuran-5-carboxylic acid scaffold. J Med Chem56:832-42 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Low molecular weight phosphotyrosine protein phosphatase |
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| Name: | Low molecular weight phosphotyrosine protein phosphatase |
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| Synonyms: | 3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c |
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| Type: | n/a |
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| Mol. Mass.: | 18042.81 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P24666 |
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| Residue: | 158 |
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| Sequence: | MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRG
QSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSY
DPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
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| BDBM50425808 |
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| n/a |
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| Name | BDBM50425808 |
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| Synonyms: | CHEMBL2316906 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H12F2O4 |
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| Mol. Mass. | 390.3358 |
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| SMILES | OC(=O)c1cc2c(C#Cc3cc(F)cc(F)c3)c(oc2cc1O)-c1ccccc1 |
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| Structure | 
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