| Reaction Details |
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 | Report a problem with these data |
| Target | Hepatocyte growth factor |
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| Ligand | BDBM50428279 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_946456 (CHEMBL2340053) |
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| Kd | 1950±n/a nM |
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| Citation |  Liang, Z; Ai, J; Ding, X; Peng, X; Zhang, D; Zhang, R; Wang, Y; Liu, F; Zheng, M; Jiang, H; Liu, H; Geng, M; Luo, C Anthraquinone Derivatives as Potent Inhibitors of c-Met Kinase and the Extracellular Signaling Pathway. ACS Med Chem Lett4:408-13 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Hepatocyte growth factor |
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| Name: | Hepatocyte growth factor |
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| Synonyms: | HGF | HGF_HUMAN | HPTA |
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| Type: | PROTEIN |
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| Mol. Mass.: | 83154.05 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_946456 |
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| Residue: | 728 |
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| Sequence: | MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP
RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP
HRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCADNTMNDTDVPL
ETTECIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGS
ESPWCFTTDPNIRVGYCSQIPNCDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNME
DLHRHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVNL
DHPVISCAKTKQLRVVNGIPTRTNIGWMVSLRYRNKHICGGSLIKESWVLTARQCFPSRD
LKDYEAWLGIHDVHGRGDEKCKQVLNVSQLVYGPEGSDLVLMKLARPAVLDDFVSTIDLP
NYGCTIPEKTSCSVYGWGYTGLINYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAG
AEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII
LTYKVPQS
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| BDBM50428279 |
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| n/a |
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| Name | BDBM50428279 |
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| Synonyms: | CHEMBL2337901 |
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| Type | Small organic molecule |
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| Emp. Form. | C40H24N4O10S2 |
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| Mol. Mass. | 784.77 |
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| SMILES | Nc1c2C(=O)c3ccccc3C(=O)c2c(Nc2ccc(cc2)-c2ccc(Nc3cc(c(N)c4C(=O)c5ccccc5C(=O)c34)S([O-])(=O)=O)cc2)cc1S([O-])(=O)=O |
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| Structure | 
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