| Reaction Details |
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 | Report a problem with these data |
| Target | Thymidylate kinase |
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| Ligand | BDBM50428613 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_946051 (CHEMBL2342088) |
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| IC50 | >200000±n/a nM |
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| Citation |  Martínez-Botella, G; Loch, JT; Green, OM; Kawatkar, SP; Olivier, NB; Boriack-Sjodin, PA; Keating, TA Sulfonylpiperidines as novel, antibacterial inhibitors of Gram-positive thymidylate kinase (TMK). Bioorg Med Chem Lett23:169-73 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Thymidylate kinase |
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| Name: | Thymidylate kinase |
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| Synonyms: | CDC8 | DTYMK | KTHY_HUMAN | TMPK | TYMK |
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| Type: | PROTEIN |
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| Mol. Mass.: | 23824.09 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_946051 |
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| Residue: | 212 |
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| Sequence: | MAARRGALIVLEGVDRAGKSTQSRKLVEALCAAGHRAELLRFPERSTEIGKLLSSYLQKK
SDVEDHSVHLLFSANRWEQVPLIKEKLSQGVTLVVDRYAFSGVAFTGAKENFSLDWCKQP
DVGLPKPDLVLFLQLQLADAAKRGAFGHERYENGAFQERALRCFHQLMKDTTLNWKMVDA
SKSIEAVHEDIRVLSEDAIRTATEKPLGELWK
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| BDBM50428613 |
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| n/a |
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| Name | BDBM50428613 |
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| Synonyms: | CHEMBL2331747 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H22ClN3O6S |
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| Mol. Mass. | 491.945 |
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| SMILES | Cc1cn([C@H]2CCCN(C2)S(=O)(=O)c2ccc(O)c(Oc3cccc(Cl)c3)c2)c(=O)[nH]c1=O |r| |
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| Structure | 
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