| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(2) dopamine receptor |
|---|
| Ligand | BDBM50429067 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_943179 (CHEMBL2346210) |
|---|
| Ki | 12±n/a nM |
|---|
| Citation |  Giovanni, A; Roehr, J; Dwyer, S; Neuenschwander, K; Scotese, A; Moorcroft, ND; Davis, L; Gao, Z Design and synthesis of D1 agonist/D2 antagonist for treatment of schizophrenia. Bioorg Med Chem Lett23:1498-501 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(2) dopamine receptor |
|---|
| Name: | D(2) dopamine receptor |
|---|
| Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 |
|---|
| Type: | Cell-surface receptors |
|---|
| Mol. Mass.: | 50647.10 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P14416 |
|---|
| Residue: | 443 |
|---|
| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
|
|
|
|---|
| BDBM50429067 |
|---|
| n/a |
|---|
| Name | BDBM50429067 |
|---|
| Synonyms: | CHEMBL2335737 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H22ClNO2 |
|---|
| Mol. Mass. | 343.847 |
|---|
| SMILES | Cc1cc2CCN3CC[C@@](O)(C[C@@H]3c2cc1O)c1ccc(Cl)cc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
