| Reaction Details |
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 | Report a problem with these data |
| Target | Acid ceramidase |
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| Ligand | BDBM29080 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_949260 (CHEMBL2346136) |
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| Ki | 500000±n/a nM |
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| Citation |  Pizzirani, D; Pagliuca, C; Realini, N; Branduardi, D; Bottegoni, G; Mor, M; Bertozzi, F; Scarpelli, R; Piomelli, D; Bandiera, T Discovery of a new class of highly potent inhibitors of acid ceramidase: synthesis and structure-activity relationship (SAR). J Med Chem56:3518-30 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Acid ceramidase |
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| Name: | Acid ceramidase |
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| Synonyms: | ASAH | ASAH1 | ASAH1_HUMAN | Acid ceramidase | Acid ceramidase (AC) |
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| Type: | Enzyme |
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| Mol. Mass.: | 44662.65 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q13510 |
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| Residue: | 395 |
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| Sequence: | MPGRSCVALVLLAAAVSCAVAQHAPPWTEDCRKSTYPPSGPTYRGAVPWYTINLDLPPYK
RWHELMLDKAPVLKVIVNSLKNMINTFVPSGKIMQVVDEKLPGLLGNFPGPFEEEMKGIA
AVTDIPLGEIISFNIFYELFTICTSIVAEDKKGHLIHGRNMDFGVFLGWNINNDTWVITE
QLKPLTVNLDFQRNNKTVFKASSFAGYVGMLTGFKPGLFSLTLNERFSINGGYLGILEWI
LGKKDVMWIGFLTRTVLENSTSYEEAKNLLTKTKILAPAYFILGGNQSGEGCVITRDRKE
SLDVYELDAKQGRWYVVQTNYDRWKHPFFLDDRRTPAKMCLNRTSQENISFETMYDVLST
KPVLNKLTVYTTLIDVTKGQFETYLRDCPDPCIGW
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| BDBM29080 |
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| n/a |
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| Name | BDBM29080 |
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| Synonyms: | CHEMBL280065 | N-oleoylethanolamine | Oleamide MEA | Oleoyl monoethanolamide | Oleoylethanolamide (OEA) |
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| Type | n/a |
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| Emp. Form. | C20H39NO2 |
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| Mol. Mass. | 325.5292 |
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| SMILES | CCCCCCCC\C=C/CCCCCCCC(=O)NCCO |
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| Structure | 
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