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TargetD-amino-acid oxidase
LigandBDBM36181
Substrate/Competitorn/a
Meas. Tech.ChEMBL_957002 (CHEMBL2378384)
Kd 2300±n/a nM
Citation Hopkins, SCHeffernan, MLSaraswat, LDBowen, CAMelnick, LHardy, LWOrsini, MAAllen, MSKoch, PSpear, KLFoglesong, RJSoukri, MChytil, MFang, QKJones, SWVarney, MAPanatier, AOliet, SHPollegioni, LPiubelli, LMolla, GNardini, MLarge, TH Structural, kinetic, and pharmacodynamic mechanisms of D-amino acid oxidase inhibition by small molecules. J Med Chem56:3710-24 (2013) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
D-amino-acid oxidase
Name:D-amino-acid oxidase
Synonyms:D-amino-acid oxidase (DAAO) | DAAO | DAMOX | DAO | OXDA_HUMAN
Type:Homodimer
Mol. Mass.:39476.06
Organism:Homo sapiens (Human)
Description:P14920
Residue:347
Sequence:
MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAGLWQPYLSDPN
NPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFRKLTPR
ELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEEVAREGADVIVN
CTGVWAGALQRDPLLQPGRGQIMKVDAPWMKHFILTHDPERGIYNSPYIIPGTQTVTLGG
IFQLGNWSELNNIQDHNTIWEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGP
SNTEVIHNYGHGGYGLTIHWGCALEAAKLFGRILEEKKLSRMPPSHL
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  Blast E-value cutoff:
BDBM36181
n/a
NameBDBM36181
Synonyms:SODIUM BENZOATE | benzoate | benzoic acid | benzoic acid-d5
TypeGuest
Emp. Form.C7H5O2
Mol. Mass.121.1139
SMILES[O-]C(=O)c1ccccc1
Structure
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