| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Glucose-dependent insulinotropic receptor |
|---|
| Ligand | BDBM50420863 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_959597 (CHEMBL2382542) |
|---|
| IC50 | 129±n/a nM |
|---|
| Citation |  Scott, JS; Brocklehurst, KJ; Brown, HS; Clarke, DS; Coe, H; Groombridge, SD; Laber, D; MacFaul, PA; McKerrecher, D; Schofield, P Conformational restriction in a series of GPR119 agonists: differences in pharmacology between mouse and human. Bioorg Med Chem Lett23:3175-9 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Glucose-dependent insulinotropic receptor |
|---|
| Name: | Glucose-dependent insulinotropic receptor |
|---|
| Synonyms: | GP119_MOUSE | Gpr119 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 37009.07 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_1506420 |
|---|
| Residue: | 335 |
|---|
| Sequence: | MESSFSFGVILAVLTILIIAVNALVVVAMLLSIYKNDGVGLCFTLNLAVADTLIGVAISG
LVTDQLSSSAQHTQKTLCSLRMAFVTSSAAASVLTVMLIAFDRYLAIKQPLRYFQIMNGL
VAGACIAGLWLVSYLIGFLPLGVSIFQQTTYHGPCSFFAVFHPRFVLTLSCAGFFPAVLL
FVFFYCDMLKIASVHSQQIRKMEHAGAMAGAYRPPRSVNDFKAVRTIAVLIGSFTLSWSP
FLITSIVQVACHKCCLYQVLEKYLWLLGVGNSLLNPLIYAYWQREVRQQLYHMALGVKKF
FTSILLLLPARNRGPERTRESAYHIVTISHPELDG
|
|
|
|---|
| BDBM50420863 |
|---|
| n/a |
|---|
| Name | BDBM50420863 |
|---|
| Synonyms: | CHEMBL2086660 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H30N4O5S |
|---|
| Mol. Mass. | 462.562 |
|---|
| SMILES | C[C@@H]1CN(CCN1c1ncc(OCc2ccc(cc2)S(C)(=O)=O)cn1)C(=O)OC(C)(C)C |r| |
|---|
| Structure | 
|
|---|
Search and Browse
