| Reaction Details |
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 | Report a problem with these data |
| Target | Nuclear receptor subfamily 1 group D member 1 |
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| Ligand | BDBM50366239 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_958222 (CHEMBL2384565) |
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| EC50 | >50000±n/a nM |
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| Citation |  Trump, RP; Bresciani, S; Cooper, AW; Tellam, JP; Wojno, J; Blaikley, J; Orband-Miller, LA; Kashatus, JA; Boudjelal, M; Dawson, HC; Loudon, A; Ray, D; Grant, D; Farrow, SN; Willson, TM; Tomkinson, NC Optimized chemical probes for REV-ERBa. J Med Chem56:4729-37 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Nuclear receptor subfamily 1 group D member 1 |
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| Name: | Nuclear receptor subfamily 1 group D member 1 |
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| Synonyms: | EAR-1 | EAR1 | HREV | NR1D1 | NR1D1_HUMAN | Rev-erbA-alpha | THRAL | V-erbA-related protein 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 66822.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_958222 |
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| Residue: | 614 |
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| Sequence: | MTTLDSNNNTGGVITYIGSSGSSPSRTSPESLYSDNSNGSFQSLTQGCPTYFPPSPTGSL
TQDPARSFGSIPPSLSDDGSPSSSSSSSSSSSSFYNGSPPGSLQVAMEDSSRVSPSKSTS
NITKLNGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRI
NRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMNLANNQLSSQCPLETS
PTQHPTPGPMGPSPPPAPVPSPLVGFSQFPQQLTPPRSPSPEPTVEDVISQVARAHREIF
TYAHDKLGSSPGNFNANHASGSPPATTPHRWENQGCPPAPNDNNTLAAQRHNEALNGLRQ
APSSYPPTWPPGPAHHSCHQSNSNGHRLCPTHVYAAPEGKAPANSPRQGNSKNVLLACPM
NMYPHGRSGRTVQEIWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVL
MVRFASLFNVKDQTVMFLSRTTYSLQELGAMGMGDLLSAMFDFSEKLNSLALTEEELGLF
TAVVLVSADRSGMENSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNN
MHSEKLLSFRVDAQ
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| BDBM50366239 |
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| n/a |
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| Name | BDBM50366239 |
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| Synonyms: | CHEMBL1961797 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H31ClN4O3S |
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| Mol. Mass. | 479.035 |
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| SMILES | CCCCCNC(=O)N1CCC(CN(Cc2ccc(s2)[N+]([O-])=O)Cc2ccc(Cl)cc2)C1 |
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| Structure | 
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