| Reaction Details |
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 | Report a problem with these data |
| Target | Steroid hormone receptor ERR1 |
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| Ligand | BDBM50434098 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_958456 (CHEMBL2383097) |
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| IC50 | 41±n/a nM |
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| Citation |  Xu, S; Zhuang, X; Pan, X; Zhang, Z; Duan, L; Liu, Y; Zhang, L; Ren, X; Ding, K 1-Phenyl-4-benzoyl-1H-1,2,3-triazoles as orally bioavailable transcriptional function suppressors of estrogen-related receptora. J Med Chem56:4631-40 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Steroid hormone receptor ERR1 |
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| Name: | Steroid hormone receptor ERR1 |
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| Synonyms: | ERR-alpha | ERR1 | ERR1_HUMAN | ESRL1 | ESRRA | Estrogen receptor-like 1 | Estrogen-Related Receptor, alpha | Estrogen-related receptor alpha | NR3B1 | Nuclear receptor subfamily 3 group B member 1 | Steroid hormone receptor ERR1 | Steroid hormone receptor ERR1 alpha | Steroid hormone receptor ERR1/Estrogen-related receptor alpha (ERRa) | von Hippel-Lindau disease tumor suppressor/Steroid hormone receptor ERR1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 45508.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1499891 |
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| Residue: | 423 |
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| Sequence: | MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAG
PGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNE
CEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGP
LAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTI
SWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAA
GLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALL
EYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEA
MMD
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| BDBM50434098 |
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| n/a |
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| Name | BDBM50434098 |
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| Synonyms: | CHEMBL2381477 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H18N4O |
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| Mol. Mass. | 306.3617 |
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| SMILES | CC(C)c1ccc(cc1)-n1cc(nn1)C(=O)c1ccccc1N |
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| Structure | 
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