| Reaction Details |
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 | Report a problem with these data |
| Target | Dipeptidyl peptidase 9 |
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| Ligand | BDBM50440469 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_982812 (CHEMBL2429189) |
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| IC50 | >100000±n/a nM |
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| Citation |  Xie, H; Zeng, L; Zeng, S; Lu, X; Zhao, X; Zhang, G; Tu, Z; Xu, H; Yang, L; Zhang, X; Wang, S; Hu, W Highly potent dipeptidyl peptidase IV inhibitors derived from Alogliptin through pharmacophore hybridization and lead optimization. Eur J Med Chem68:312-20 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dipeptidyl peptidase 9 |
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| Name: | Dipeptidyl peptidase 9 |
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| Synonyms: | DPP9 | DPP9_HUMAN | DPRP-2 | DPRP2 | Dipeptidyl peptidase 9 (DDP9) | Dipeptidyl peptidase 9 (DPP-9) | Dipeptidyl peptidase 9 (DPP9) | Dipeptidyl peptidase IV-related protein 2 | Dipeptidyl peptidase IX | Dipeptidyl peptidase IX (DDP-IX) | Dipeptidyl peptidase-like protein 9 |
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| Type: | Enzyme |
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| Mol. Mass.: | 98260.70 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q86TI2 |
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| Residue: | 863 |
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| Sequence: | MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQ
KTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGV
YSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEI
KTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAG
VATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKT
DSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRD
GKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVW
INVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFK
CPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVR
LTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAAS
CPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIK
YLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFID
LSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHG
YEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERH
SIRCPESGEHYEVTLLHFLQEYL
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| BDBM50440469 |
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| n/a |
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| Name | BDBM50440469 |
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| Synonyms: | CHEMBL2425884 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H22N6O2 |
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| Mol. Mass. | 354.4063 |
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| SMILES | CC#CCn1c(cc(=O)n(Cc2ncccn2)c1=O)N1CCC[C@@H](N)C1 |r| |
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| Structure | 
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