| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein phosphatase 10 |
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| Ligand | BDBM50441297 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_984915 (CHEMBL2432854) |
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| Ki | 340000±n/a nM |
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| Citation |  Baguley, TD; Xu, HC; Chatterjee, M; Nairn, AC; Lombroso, PJ; Ellman, JA Substrate-based fragment identification for the development of selective, nonpeptidic inhibitors of striatal-enriched protein tyrosine phosphatase. J Med Chem56:7636-50 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dual specificity protein phosphatase 10 |
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| Name: | Dual specificity protein phosphatase 10 |
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| Synonyms: | DUS10_HUMAN | DUSP10 | Dual specificity protein phosphatase 10 | MAP kinase phosphatase 5 | MKP-5 | MKP5 | Mitogen-activated protein kinase phosphatase 5 | Mitogen-activated protein kinase phosphatase 5 (MKP5) |
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| Type: | Enzyme |
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| Mol. Mass.: | 52649.12 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9Y6W6 |
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| Residue: | 482 |
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| Sequence: | MPPSPLDDRVVVALSRPVRPQDLNLCLDSSYLGSANPGSNSHPPVIATTVVSLKAANLTY
MPSSSGSARSLNCGCSSASCCTVATYDKDNQAQTQAIAAGTTTTAIGTSTTCPANQMVNN
NENTGSLSPSSGVGSPVSGTPKQLASIKIIYPNDLAKKMTKCSKSHLPSQGPVIIDCRPF
MEYNKSHIQGAVHINCADKISRRRLQQGKITVLDLISCREGKDSFKRIFSKEIIVYDENT
NEPSRVMPSQPLHIVLESLKREGKEPLVLKGGLSSFKQNHENLCDNSLQLQECREVGGGA
SAASSLLPQPIPTTPDIENAELTPILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTHLPL
YHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVI
AYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRILTPKLMGVET
VV
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| BDBM50441297 |
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| n/a |
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| Name | BDBM50441297 |
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| Synonyms: | CHEMBL2431664 | CHEMBL2431666 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H17Cl2O5P |
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| Mol. Mass. | 439.226 |
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| SMILES | O[C@H](c1cccc(c1)-c1ccc(cc1)C(=O)P(O)(O)O)c1ccc(Cl)c(Cl)c1 |r| |
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| Structure | 
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