Found 531 hits with Last Name = 'baguley' and Initial = 'td' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50103445
(CHEMBL3398243)Show InChI InChI=1S/C7H3F3S5/c8-7(9,10)4-1-2-5-6(3-4)12-14-15-13-11-5/h1-3H | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 109 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of STEP (unknown origin) in absence of GSH by p-nitrophenyl phosphate hydrolysis assay |
Bioorg Med Chem Lett 25: 1044-6 (2015)
Article DOI: 10.1016/j.bmcl.2015.01.020 BindingDB Entry DOI: 10.7270/Q2QN68JF |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50067512
(CHEMBL3401893)Show InChI InChI=1S/C7H4F3NS5/c8-7(9,10)3-1-4(11)6-5(2-3)12-14-16-15-13-6/h1-2H,11H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 115 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of STEP (unknown origin) in absence of GSH by p-nitrophenyl phosphate hydrolysis assay |
Bioorg Med Chem Lett 25: 1044-6 (2015)
Article DOI: 10.1016/j.bmcl.2015.01.020 BindingDB Entry DOI: 10.7270/Q2QN68JF |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50103444
(CHEMBL3398244)Show InChI InChI=1S/C7H7NS5.ClH/c1-4-2-5(8)7-6(3-4)9-11-13-12-10-7;/h2-3H,8H2,1H3;1H | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 116 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of STEP (unknown origin) in absence of GSH by p-nitrophenyl phosphate hydrolysis assay |
Bioorg Med Chem Lett 25: 1044-6 (2015)
Article DOI: 10.1016/j.bmcl.2015.01.020 BindingDB Entry DOI: 10.7270/Q2QN68JF |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50103448
(CHEMBL3398247)Show InChI InChI=1S/C9H6F3NOS5/c1-4(14)13-6-2-5(9(10,11)12)3-7-8(6)16-18-19-17-15-7/h2-3H,1H3,(H,13,14) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 123 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of STEP (unknown origin) in absence of GSH by p-nitrophenyl phosphate hydrolysis assay |
Bioorg Med Chem Lett 25: 1044-6 (2015)
Article DOI: 10.1016/j.bmcl.2015.01.020 BindingDB Entry DOI: 10.7270/Q2QN68JF |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50103447
(CHEMBL3398250)Show SMILES Cl.Cl.Nc1cc(cc2SSSc3c(N)cc(cc3SSSc12)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C14H8F6N2S6.2ClH/c15-13(16,17)5-1-7(21)11-9(3-5)23-28-26-12-8(22)2-6(14(18,19)20)4-10(12)24-27-25-11;;/h1-4H,21-22H2;2*1H | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 124 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of STEP (unknown origin) in absence of GSH by p-nitrophenyl phosphate hydrolysis assay |
Bioorg Med Chem Lett 25: 1044-6 (2015)
Article DOI: 10.1016/j.bmcl.2015.01.020 BindingDB Entry DOI: 10.7270/Q2QN68JF |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50103450
(CHEMBL3398249)Show InChI InChI=1S/C14H10F3NS5/c15-14(16,17)10-6-11(18-8-9-4-2-1-3-5-9)13-12(7-10)19-21-23-22-20-13/h1-7,18H,8H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 175 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of STEP (unknown origin) in absence of GSH by p-nitrophenyl phosphate hydrolysis assay |
Bioorg Med Chem Lett 25: 1044-6 (2015)
Article DOI: 10.1016/j.bmcl.2015.01.020 BindingDB Entry DOI: 10.7270/Q2QN68JF |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50103443
(CHEMBL3398245)Show InChI InChI=1S/C6H5NS5.ClH/c7-4-2-1-3-5-6(4)9-11-12-10-8-5;/h1-3H,7H2;1H | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 183 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of STEP (unknown origin) in absence of GSH by p-nitrophenyl phosphate hydrolysis assay |
Bioorg Med Chem Lett 25: 1044-6 (2015)
Article DOI: 10.1016/j.bmcl.2015.01.020 BindingDB Entry DOI: 10.7270/Q2QN68JF |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50103446
(CHEMBL3398251)Show InChI InChI=1S/C7H2F3NO2S3/c8-7(9,10)3-1-4(11(12)13)6-5(2-3)14-16-15-6/h1-2H | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of STEP (unknown origin) in absence of GSH by p-nitrophenyl phosphate hydrolysis assay |
Bioorg Med Chem Lett 25: 1044-6 (2015)
Article DOI: 10.1016/j.bmcl.2015.01.020 BindingDB Entry DOI: 10.7270/Q2QN68JF |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50103449
(CHEMBL3398248)Show InChI InChI=1S/C9H8F3NS5/c1-2-13-6-3-5(9(10,11)12)4-7-8(6)15-17-18-16-14-7/h3-4,13H,2H2,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of STEP (unknown origin) in absence of GSH by p-nitrophenyl phosphate hydrolysis assay |
Bioorg Med Chem Lett 25: 1044-6 (2015)
Article DOI: 10.1016/j.bmcl.2015.01.020 BindingDB Entry DOI: 10.7270/Q2QN68JF |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50067504
(CHEMBL3398246)Show InChI InChI=1S/C9H3F6NOS5/c10-8(11,12)3-1-4(16-7(17)9(13,14)15)6-5(2-3)18-20-22-21-19-6/h1-2H,(H,16,17) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 235 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of STEP (unknown origin) in absence of GSH by p-nitrophenyl phosphate hydrolysis assay |
Bioorg Med Chem Lett 25: 1044-6 (2015)
Article DOI: 10.1016/j.bmcl.2015.01.020 BindingDB Entry DOI: 10.7270/Q2QN68JF |
More data for this Ligand-Target Pair | |
Low molecular weight protein-tyrosine phosphatase A
(Mycobacterium tuberculosis) | BDBM50312261
((4-(4-bromo-3,5-bis(trifluoromethyl)phenylcarbamoy...)Show SMILES OP(O)(=O)C(F)(F)c1ccc(cc1)C(=O)Nc1cc(c(Br)c(c1)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C16H9BrF8NO4P/c17-12-10(14(18,19)20)5-9(6-11(12)15(21,22)23)26-13(27)7-1-3-8(4-2-7)16(24,25)31(28,29)30/h1-6H,(H,26,27)(H2,28,29,30) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PtpA |
Bioorg Med Chem Lett 19: 6851-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.090 BindingDB Entry DOI: 10.7270/Q21G0MDK |
More data for this Ligand-Target Pair | |
Low molecular weight protein-tyrosine phosphatase A
(Mycobacterium tuberculosis) | BDBM50312266
((4-(3-(3,5-bis(trifluoromethyl)phenyl)ureido)pheny...)Show SMILES OP(O)(=O)C(F)(F)c1ccc(NC(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1 Show InChI InChI=1S/C16H11F8N2O4P/c17-14(18,19)9-5-10(15(20,21)22)7-12(6-9)26-13(27)25-11-3-1-8(2-4-11)16(23,24)31(28,29)30/h1-7H,(H2,25,26,27)(H2,28,29,30) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PtpA |
Bioorg Med Chem Lett 19: 6851-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.090 BindingDB Entry DOI: 10.7270/Q21G0MDK |
More data for this Ligand-Target Pair | |
Low molecular weight protein-tyrosine phosphatase A
(Mycobacterium tuberculosis) | BDBM50312260
((4-(3,5-bis(trifluoromethyl)phenylcarbamoyl)phenyl...)Show SMILES OP(O)(=O)C(F)(F)c1ccc(cc1)C(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C16H10F8NO4P/c17-14(18,19)10-5-11(15(20,21)22)7-12(6-10)25-13(26)8-1-3-9(4-2-8)16(23,24)30(27,28)29/h1-7H,(H,25,26)(H2,27,28,29) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PtpA |
Bioorg Med Chem Lett 19: 6851-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.090 BindingDB Entry DOI: 10.7270/Q21G0MDK |
More data for this Ligand-Target Pair | |
Low molecular weight protein-tyrosine phosphatase A
(Mycobacterium tuberculosis) | BDBM50312259
((4-(4-bromo-3-(trifluoromethyl)phenylcarbamoyl)phe...)Show SMILES OP(O)(=O)C(F)(F)c1ccc(cc1)C(=O)Nc1ccc(Br)c(c1)C(F)(F)F Show InChI InChI=1S/C15H10BrF5NO4P/c16-12-6-5-10(7-11(12)14(17,18)19)22-13(23)8-1-3-9(4-2-8)15(20,21)27(24,25)26/h1-7H,(H,22,23)(H2,24,25,26) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PtpA |
Bioorg Med Chem Lett 19: 6851-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.090 BindingDB Entry DOI: 10.7270/Q21G0MDK |
More data for this Ligand-Target Pair | |
Low molecular weight protein-tyrosine phosphatase A
(Mycobacterium tuberculosis) | BDBM50312258
((4-(4-chloro-3-(trifluoromethyl)phenylcarbamoyl)ph...)Show SMILES OP(O)(=O)C(F)(F)c1ccc(cc1)C(=O)Nc1ccc(Cl)c(c1)C(F)(F)F Show InChI InChI=1S/C15H10ClF5NO4P/c16-12-6-5-10(7-11(12)14(17,18)19)22-13(23)8-1-3-9(4-2-8)15(20,21)27(24,25)26/h1-7H,(H,22,23)(H2,24,25,26) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PtpA |
Bioorg Med Chem Lett 19: 6851-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.090 BindingDB Entry DOI: 10.7270/Q21G0MDK |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50441296
(CHEMBL2431665 | CHEMBL2431667)Show SMILES O[C@@H](c1cccc(c1)-c1ccc(cc1)C(=O)P(O)(O)O)c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C20H17Cl2O5P/c21-17-9-8-16(11-18(17)22)19(23)15-3-1-2-14(10-15)12-4-6-13(7-5-12)20(24)28(25,26)27/h1-11,19,23,25-28H/t19-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 7.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysis |
J Med Chem 56: 7636-50 (2013)
Article DOI: 10.1021/jm401037h BindingDB Entry DOI: 10.7270/Q2HH6MHW |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50441302
(CHEMBL2431688)Show SMILES OP(O)(O)C(=O)c1ccc(cc1)-c1cccc(Cc2ccc(Cl)c(Cl)c2)c1 Show InChI InChI=1S/C20H17Cl2O4P/c21-18-9-4-14(12-19(18)22)10-13-2-1-3-17(11-13)15-5-7-16(8-6-15)20(23)27(24,25)26/h1-9,11-12,24-27H,10H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 8.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysis |
J Med Chem 56: 7636-50 (2013)
Article DOI: 10.1021/jm401037h BindingDB Entry DOI: 10.7270/Q2HH6MHW |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50441297
(CHEMBL2431664 | CHEMBL2431666)Show SMILES O[C@H](c1cccc(c1)-c1ccc(cc1)C(=O)P(O)(O)O)c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C20H17Cl2O5P/c21-17-9-8-16(11-18(17)22)19(23)15-3-1-2-14(10-15)12-4-6-13(7-5-12)20(24)28(25,26)27/h1-11,19,23,25-28H/t19-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 8.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysis |
J Med Chem 56: 7636-50 (2013)
Article DOI: 10.1021/jm401037h BindingDB Entry DOI: 10.7270/Q2HH6MHW |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50441304
(CHEMBL2431686)Show SMILES OP(O)(=O)C(F)(F)c1ccc(cc1)-c1cccc(Cc2ccc(Cl)c(Cl)c2)c1 Show InChI InChI=1S/C20H15Cl2F2O3P/c21-18-9-4-14(12-19(18)22)10-13-2-1-3-16(11-13)15-5-7-17(8-6-15)20(23,24)28(25,26)27/h1-9,11-12H,10H2,(H2,25,26,27) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 9.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysis |
J Med Chem 56: 7636-50 (2013)
Article DOI: 10.1021/jm401037h BindingDB Entry DOI: 10.7270/Q2HH6MHW |
More data for this Ligand-Target Pair | |
Low molecular weight protein-tyrosine phosphatase A
(Mycobacterium tuberculosis) | BDBM50312256
((4-(4-bromophenylcarbamoyl)phenyl)difluoromethylph...)Show SMILES OP(O)(=O)C(F)(F)c1ccc(cc1)C(=O)Nc1ccc(Br)cc1 Show InChI InChI=1S/C14H11BrF2NO4P/c15-11-5-7-12(8-6-11)18-13(19)9-1-3-10(4-2-9)14(16,17)23(20,21)22/h1-8H,(H,18,19)(H2,20,21,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.03E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PtpA |
Bioorg Med Chem Lett 19: 6851-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.090 BindingDB Entry DOI: 10.7270/Q21G0MDK |
More data for this Ligand-Target Pair | |
Low molecular weight protein-tyrosine phosphatase A
(Mycobacterium tuberculosis) | BDBM50312252
(CHEMBL1080488 | difluoro(4-(3-(trifluoromethyl)phe...)Show SMILES OP(O)(=O)C(F)(F)c1ccc(cc1)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C15H11F5NO4P/c16-14(17,18)11-2-1-3-12(8-11)21-13(22)9-4-6-10(7-5-9)15(19,20)26(23,24)25/h1-8H,(H,21,22)(H2,23,24,25) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.07E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PtpA |
Bioorg Med Chem Lett 19: 6851-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.090 BindingDB Entry DOI: 10.7270/Q21G0MDK |
More data for this Ligand-Target Pair | |
Low molecular weight protein-tyrosine phosphatase A
(Mycobacterium tuberculosis) | BDBM50312257
(CHEMBL1080667 | difluoro(4-(4-fluoro-3-(trifluorom...)Show SMILES OP(O)(=O)C(F)(F)c1ccc(cc1)C(=O)Nc1ccc(F)c(c1)C(F)(F)F Show InChI InChI=1S/C15H10F6NO4P/c16-12-6-5-10(7-11(12)14(17,18)19)22-13(23)8-1-3-9(4-2-8)15(20,21)27(24,25)26/h1-7H,(H,22,23)(H2,24,25,26) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.14E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PtpA |
Bioorg Med Chem Lett 19: 6851-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.090 BindingDB Entry DOI: 10.7270/Q21G0MDK |
More data for this Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Homo sapiens (Human)) | BDBM50312261
((4-(4-bromo-3,5-bis(trifluoromethyl)phenylcarbamoy...)Show SMILES OP(O)(=O)C(F)(F)c1ccc(cc1)C(=O)Nc1cc(c(Br)c(c1)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C16H9BrF8NO4P/c17-12-10(14(18,19)20)5-9(6-11(12)15(21,22)23)26-13(27)7-1-3-8(4-2-7)16(24,25)31(28,29)30/h1-6H,(H,26,27)(H2,28,29,30) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.48E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human HCPTPA |
Bioorg Med Chem Lett 19: 6851-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.090 BindingDB Entry DOI: 10.7270/Q21G0MDK |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50441303
(CHEMBL2431687)Show SMILES OC(c1cccc(c1)-c1ccc(cc1)C(F)(F)P(O)(O)=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C20H15Cl2F2O4P/c21-17-9-6-15(11-18(17)22)19(25)14-3-1-2-13(10-14)12-4-7-16(8-5-12)20(23,24)29(26,27)28/h1-11,19,25H,(H2,26,27,28) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysis |
J Med Chem 56: 7636-50 (2013)
Article DOI: 10.1021/jm401037h BindingDB Entry DOI: 10.7270/Q2HH6MHW |
More data for this Ligand-Target Pair | |
Low molecular weight protein-tyrosine phosphatase A
(Mycobacterium tuberculosis) | BDBM50312255
((4-(4-chlorophenylcarbamoyl)phenyl)difluoromethylp...)Show SMILES OP(O)(=O)C(F)(F)c1ccc(cc1)C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C14H11ClF2NO4P/c15-11-5-7-12(8-6-11)18-13(19)9-1-3-10(4-2-9)14(16,17)23(20,21)22/h1-8H,(H,18,19)(H2,20,21,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.68E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PtpA |
Bioorg Med Chem Lett 19: 6851-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.090 BindingDB Entry DOI: 10.7270/Q21G0MDK |
More data for this Ligand-Target Pair | |
Low molecular weight protein-tyrosine phosphatase A
(Mycobacterium tuberculosis) | BDBM50312251
((4-(3-bromophenylcarbamoyl)phenyl)difluoromethylph...)Show SMILES OP(O)(=O)C(F)(F)c1ccc(cc1)C(=O)Nc1cccc(Br)c1 Show InChI InChI=1S/C14H11BrF2NO4P/c15-11-2-1-3-12(8-11)18-13(19)9-4-6-10(7-5-9)14(16,17)23(20,21)22/h1-8H,(H,18,19)(H2,20,21,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.82E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PtpA |
Bioorg Med Chem Lett 19: 6851-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.090 BindingDB Entry DOI: 10.7270/Q21G0MDK |
More data for this Ligand-Target Pair | |
Low molecular weight protein-tyrosine phosphatase A
(Mycobacterium tuberculosis) | BDBM50312254
(CHEMBL1080494 | difluoro(4-(4-(trifluoromethyl)phe...)Show SMILES OP(O)(=O)C(F)(F)c1ccc(cc1)C(=O)Nc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C15H11F5NO4P/c16-14(17,18)10-5-7-12(8-6-10)21-13(22)9-1-3-11(4-2-9)15(19,20)26(23,24)25/h1-8H,(H,21,22)(H2,23,24,25) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.85E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PtpA |
Bioorg Med Chem Lett 19: 6851-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.090 BindingDB Entry DOI: 10.7270/Q21G0MDK |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50441305
(CHEMBL2431685)Show SMILES OP(O)(=O)C(F)(F)c1ccc(cc1)-c1cccc(Cc2ccc(Cl)cc2)c1 Show InChI InChI=1S/C20H16ClF2O3P/c21-19-10-4-14(5-11-19)12-15-2-1-3-17(13-15)16-6-8-18(9-7-16)20(22,23)27(24,25)26/h1-11,13H,12H2,(H2,24,25,26) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysis |
J Med Chem 56: 7636-50 (2013)
Article DOI: 10.1021/jm401037h BindingDB Entry DOI: 10.7270/Q2HH6MHW |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50441298
(CHEMBL2431708)Show SMILES Oc1c(cccc1-c1cccc(c1)C(F)(F)P(O)(O)=O)C1CCCCC1 Show InChI InChI=1S/C19H21F2O4P/c20-19(21,26(23,24)25)15-9-4-8-14(12-15)17-11-5-10-16(18(17)22)13-6-2-1-3-7-13/h4-5,8-13,22H,1-3,6-7H2,(H2,23,24,25) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysis |
J Med Chem 56: 7636-50 (2013)
Article DOI: 10.1021/jm401037h BindingDB Entry DOI: 10.7270/Q2HH6MHW |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Low molecular weight protein-tyrosine phosphatase A
(Mycobacterium tuberculosis) | BDBM50312253
(CHEMBL1075857 | difluoro(4-(4-fluorophenylcarbamoy...)Show SMILES OP(O)(=O)C(F)(F)c1ccc(cc1)C(=O)Nc1ccc(F)cc1 Show InChI InChI=1S/C14H11F3NO4P/c15-11-5-7-12(8-6-11)18-13(19)9-1-3-10(4-2-9)14(16,17)23(20,21)22/h1-8H,(H,18,19)(H2,20,21,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.27E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PtpA |
Bioorg Med Chem Lett 19: 6851-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.090 BindingDB Entry DOI: 10.7270/Q21G0MDK |
More data for this Ligand-Target Pair | |
Low molecular weight protein-tyrosine phosphatase A
(Mycobacterium tuberculosis) | BDBM50312244
(CHEMBL1080018 | difluoro(4-(phenylcarbamoyl)phenyl...)Show InChI InChI=1S/C14H12F2NO4P/c15-14(16,22(19,20)21)11-8-6-10(7-9-11)13(18)17-12-4-2-1-3-5-12/h1-9H,(H,17,18)(H2,19,20,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PtpA |
Bioorg Med Chem Lett 19: 6851-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.090 BindingDB Entry DOI: 10.7270/Q21G0MDK |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50441322
(CHEMBL2431707)Show SMILES Oc1c(cccc1-c1cccc(c1)C(F)(F)P(O)(O)=O)C1CCCC1 Show InChI InChI=1S/C18H19F2O4P/c19-18(20,25(22,23)24)14-8-3-7-13(11-14)16-10-4-9-15(17(16)21)12-5-1-2-6-12/h3-4,7-12,21H,1-2,5-6H2,(H2,22,23,24) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysis |
J Med Chem 56: 7636-50 (2013)
Article DOI: 10.1021/jm401037h BindingDB Entry DOI: 10.7270/Q2HH6MHW |
More data for this Ligand-Target Pair | |
Low molecular weight protein-tyrosine phosphatase A
(Mycobacterium tuberculosis) | BDBM50312243
(CHEMBL1080017 | difluoro(4-(thiazol-2-ylcarbamoyl)...)Show InChI InChI=1S/C11H9F2N2O4PS/c12-11(13,20(17,18)19)8-3-1-7(2-4-8)9(16)15-10-14-5-6-21-10/h1-6H,(H,14,15,16)(H2,17,18,19) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PtpA |
Bioorg Med Chem Lett 19: 6851-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.090 BindingDB Entry DOI: 10.7270/Q21G0MDK |
More data for this Ligand-Target Pair | |
Low molecular weight protein-tyrosine phosphatase A
(Mycobacterium tuberculosis) | BDBM50312250
((4-(3-chlorophenylcarbamoyl)phenyl)difluoromethylp...)Show SMILES OP(O)(=O)C(F)(F)c1ccc(cc1)C(=O)Nc1cccc(Cl)c1 Show InChI InChI=1S/C14H11ClF2NO4P/c15-11-2-1-3-12(8-11)18-13(19)9-4-6-10(7-5-9)14(16,17)23(20,21)22/h1-8H,(H,18,19)(H2,20,21,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.49E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PtpA |
Bioorg Med Chem Lett 19: 6851-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.090 BindingDB Entry DOI: 10.7270/Q21G0MDK |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50441306
(CHEMBL2431684)Show SMILES OP(O)(=O)C(F)(F)c1ccc(cc1)-c1cccc(Cc2ccc(F)cc2)c1 Show InChI InChI=1S/C20H16F3O3P/c21-19-10-4-14(5-11-19)12-15-2-1-3-17(13-15)16-6-8-18(9-7-16)20(22,23)27(24,25)26/h1-11,13H,12H2,(H2,24,25,26) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysis |
J Med Chem 56: 7636-50 (2013)
Article DOI: 10.1021/jm401037h BindingDB Entry DOI: 10.7270/Q2HH6MHW |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50441320
(CHEMBL2431670)Show SMILES Oc1c(cccc1-c1cccc(c1)C(=O)P(O)(O)O)C1CCCCC1 Show InChI InChI=1S/C19H23O5P/c20-18-16(13-6-2-1-3-7-13)10-5-11-17(18)14-8-4-9-15(12-14)19(21)25(22,23)24/h4-5,8-13,20,22-25H,1-3,6-7H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 3.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysis |
J Med Chem 56: 7636-50 (2013)
Article DOI: 10.1021/jm401037h BindingDB Entry DOI: 10.7270/Q2HH6MHW |
More data for this Ligand-Target Pair | |
Low molecular weight protein-tyrosine phosphatase A
(Mycobacterium tuberculosis) | BDBM50312249
(CHEMBL1080201 | difluoro(4-(3-fluorophenylcarbamoy...)Show SMILES OP(O)(=O)C(F)(F)c1ccc(cc1)C(=O)Nc1cccc(F)c1 Show InChI InChI=1S/C14H11F3NO4P/c15-11-2-1-3-12(8-11)18-13(19)9-4-6-10(7-5-9)14(16,17)23(20,21)22/h1-8H,(H,18,19)(H2,20,21,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4.18E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PtpA |
Bioorg Med Chem Lett 19: 6851-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.090 BindingDB Entry DOI: 10.7270/Q21G0MDK |
More data for this Ligand-Target Pair | |
Low molecular weight protein-tyrosine phosphatase A
(Mycobacterium tuberculosis) | BDBM50312242
((4-(benzylcarbamoyl)phenyl)difluoromethylphosphoni...)Show InChI InChI=1S/C15H14F2NO4P/c16-15(17,23(20,21)22)13-8-6-12(7-9-13)14(19)18-10-11-4-2-1-3-5-11/h1-9H,10H2,(H,18,19)(H2,20,21,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4.31E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PtpA |
Bioorg Med Chem Lett 19: 6851-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.090 BindingDB Entry DOI: 10.7270/Q21G0MDK |
More data for this Ligand-Target Pair | |
Low molecular weight protein-tyrosine phosphatase A
(Mycobacterium tuberculosis) | BDBM50312248
((4-(2-bromophenylcarbamoyl)phenyl)difluoromethylph...)Show InChI InChI=1S/C14H11BrF2NO4P/c15-11-3-1-2-4-12(11)18-13(19)9-5-7-10(8-6-9)14(16,17)23(20,21)22/h1-8H,(H,18,19)(H2,20,21,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4.46E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PtpA |
Bioorg Med Chem Lett 19: 6851-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.090 BindingDB Entry DOI: 10.7270/Q21G0MDK |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50441323
(CHEMBL2431706)Show SMILES Oc1c(cccc1-c1cccc(c1)C(F)(F)P(O)(O)=O)C1CCC1 Show InChI InChI=1S/C17H17F2O4P/c18-17(19,24(21,22)23)13-7-2-6-12(10-13)15-9-3-8-14(16(15)20)11-4-1-5-11/h2-3,6-11,20H,1,4-5H2,(H2,21,22,23) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysis |
J Med Chem 56: 7636-50 (2013)
Article DOI: 10.1021/jm401037h BindingDB Entry DOI: 10.7270/Q2HH6MHW |
More data for this Ligand-Target Pair | |
Low molecular weight protein-tyrosine phosphatase A
(Mycobacterium tuberculosis) | BDBM50312241
(CHEMBL1081937 | difluoro(4-(2,2,2-trifluoroethylca...)Show InChI InChI=1S/C10H9F5NO4P/c11-9(12,13)5-16-8(17)6-1-3-7(4-2-6)10(14,15)21(18,19)20/h1-4H,5H2,(H,16,17)(H2,18,19,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4.97E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PtpA |
Bioorg Med Chem Lett 19: 6851-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.090 BindingDB Entry DOI: 10.7270/Q21G0MDK |
More data for this Ligand-Target Pair | |
Low molecular weight protein-tyrosine phosphatase A
(Mycobacterium tuberculosis) | BDBM50312247
(CHEMBL1075838 | difluoro(4-(2-(trifluoromethyl)phe...)Show SMILES OP(O)(=O)C(F)(F)c1ccc(cc1)C(=O)Nc1ccccc1C(F)(F)F Show InChI InChI=1S/C15H11F5NO4P/c16-14(17,18)11-3-1-2-4-12(11)21-13(22)9-5-7-10(8-6-9)15(19,20)26(23,24)25/h1-8H,(H,21,22)(H2,23,24,25) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 5.48E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PtpA |
Bioorg Med Chem Lett 19: 6851-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.090 BindingDB Entry DOI: 10.7270/Q21G0MDK |
More data for this Ligand-Target Pair | |
Low molecular weight protein-tyrosine phosphatase A
(Mycobacterium tuberculosis) | BDBM50312240
(CHEMBL1081936 | difluoro(4-(phenethylcarbamoyl)phe...)Show InChI InChI=1S/C16H16F2NO4P/c17-16(18,24(21,22)23)14-8-6-13(7-9-14)15(20)19-11-10-12-4-2-1-3-5-12/h1-9H,10-11H2,(H,19,20)(H2,21,22,23) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 6.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PtpA |
Bioorg Med Chem Lett 19: 6851-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.090 BindingDB Entry DOI: 10.7270/Q21G0MDK |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50441321
(CHEMBL2431669)Show SMILES Oc1c(cccc1-c1cccc(c1)C(F)(F)P(O)(O)=O)C1CCCCCC1 Show InChI InChI=1S/C20H23F2O4P/c21-20(22,27(24,25)26)16-10-5-9-15(13-16)18-12-6-11-17(19(18)23)14-7-3-1-2-4-8-14/h5-6,9-14,23H,1-4,7-8H2,(H2,24,25,26) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 6.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysis |
J Med Chem 56: 7636-50 (2013)
Article DOI: 10.1021/jm401037h BindingDB Entry DOI: 10.7270/Q2HH6MHW |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50441324
(CHEMBL2431705)Show SMILES CC(C)(C)c1cccc(c1O)-c1cccc(c1)C(F)(F)P(O)(O)=O Show InChI InChI=1S/C17H19F2O4P/c1-16(2,3)14-9-5-8-13(15(14)20)11-6-4-7-12(10-11)17(18,19)24(21,22)23/h4-10,20H,1-3H3,(H2,21,22,23) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 6.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysis |
J Med Chem 56: 7636-50 (2013)
Article DOI: 10.1021/jm401037h BindingDB Entry DOI: 10.7270/Q2HH6MHW |
More data for this Ligand-Target Pair | |
Low molecular weight protein-tyrosine phosphatase A
(Mycobacterium tuberculosis) | BDBM50312231
((4-benzamidophenyl)difluoromethylphosphonic acid |...)Show InChI InChI=1S/C14H12F2NO4P/c15-14(16,22(19,20)21)11-6-8-12(9-7-11)17-13(18)10-4-2-1-3-5-10/h1-9H,(H,17,18)(H2,19,20,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 6.55E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PtpA |
Bioorg Med Chem Lett 19: 6851-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.090 BindingDB Entry DOI: 10.7270/Q21G0MDK |
More data for this Ligand-Target Pair | |
Low molecular weight protein-tyrosine phosphatase A
(Mycobacterium tuberculosis) | BDBM50312246
((4-(2-chlorophenylcarbamoyl)phenyl)difluoromethylp...)Show InChI InChI=1S/C14H11ClF2NO4P/c15-11-3-1-2-4-12(11)18-13(19)9-5-7-10(8-6-9)14(16,17)23(20,21)22/h1-8H,(H,18,19)(H2,20,21,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 6.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PtpA |
Bioorg Med Chem Lett 19: 6851-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.090 BindingDB Entry DOI: 10.7270/Q21G0MDK |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50441327
(CHEMBL2431702)Show SMILES CC(C)c1cccc(c1O)-c1cccc(c1)C(F)(F)P(O)(O)=O Show InChI InChI=1S/C16H17F2O4P/c1-10(2)13-7-4-8-14(15(13)19)11-5-3-6-12(9-11)16(17,18)23(20,21)22/h3-10,19H,1-2H3,(H2,20,21,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 6.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysis |
J Med Chem 56: 7636-50 (2013)
Article DOI: 10.1021/jm401037h BindingDB Entry DOI: 10.7270/Q2HH6MHW |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 2
(Homo sapiens (Human)) | BDBM50441298
(CHEMBL2431708)Show SMILES Oc1c(cccc1-c1cccc(c1)C(F)(F)P(O)(O)=O)C1CCCCC1 Show InChI InChI=1S/C19H21F2O4P/c20-19(21,26(23,24)25)15-9-4-8-14(12-15)17-11-5-10-16(18(17)22)13-6-2-1-3-7-13/h4-5,8-13,22H,1-3,6-7H2,(H2,23,24,25) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 7.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of human TC-PTP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysis |
J Med Chem 56: 7636-50 (2013)
Article DOI: 10.1021/jm401037h BindingDB Entry DOI: 10.7270/Q2HH6MHW |
More data for this Ligand-Target Pair | |
Low molecular weight protein-tyrosine phosphatase A
(Mycobacterium tuberculosis) | BDBM50312239
((4-(cyclopentylcarbamoyl)phenyl)difluoromethylphos...)Show InChI InChI=1S/C13H16F2NO4P/c14-13(15,21(18,19)20)10-7-5-9(6-8-10)12(17)16-11-3-1-2-4-11/h5-8,11H,1-4H2,(H,16,17)(H2,18,19,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 7.24E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PtpA |
Bioorg Med Chem Lett 19: 6851-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.090 BindingDB Entry DOI: 10.7270/Q21G0MDK |
More data for this Ligand-Target Pair | |