| Reaction Details |
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 | Report a problem with these data |
| Target | Glucose-dependent insulinotropic receptor |
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| Ligand | BDBM50014376 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1350718 (CHEMBL3266103) |
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| EC50 | 67±n/a nM |
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| Citation |  Ye, XY; Morales, CL; Wang, Y; Rossi, KA; Malmstrom, SE; Abousleiman, M; Sereda, L; Apedo, A; Robl, JA; Miller, KJ; Krupinski, J; Wacker, DA Synthesis and structure-activity relationship of dihydrobenzofuran derivatives as novel human GPR119 agonists. Bioorg Med Chem Lett24:2539-45 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glucose-dependent insulinotropic receptor |
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| Name: | Glucose-dependent insulinotropic receptor |
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| Synonyms: | G-protein coupled receptor 119 (GPR119) | GP119_HUMAN | GPR119 | Glucose-dependent insulinotropic receptor |
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| Type: | Protein |
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| Mol. Mass.: | 36901.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q8TDV5 |
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| Residue: | 335 |
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| Sequence: | MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISG
LLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLKIMSGF
VAGACIAGLWLVSYLIGFLPLGIPMFQQTAYKGQCSFFAVFHPHFVLTLSCVGFFPAMLL
FVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFKALRTVSVLIGSFALSWTP
FLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKV
LTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
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| BDBM50014376 |
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| n/a |
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| Name | BDBM50014376 |
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| Synonyms: | CHEMBL3261128 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H36N4O3S |
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| Mol. Mass. | 508.675 |
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| SMILES | CCCS(=O)(=O)N1CCC(=CC1)c1ccc2OC(Cc2c1)C1CCN(CC1)c1ncc(cn1)C1CC1 |c:9| |
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| Structure | 
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