| Reaction Details |
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 | Report a problem with these data |
| Target | Aromatic-L-amino-acid decarboxylase |
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| Ligand | BDBM25525 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1363990 (CHEMBL3295577) |
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| IC50 | 200000±n/a nM |
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| Citation |  Cheng, P; Zhou, J; Qing, Z; Kang, W; Liu, S; Liu, W; Xie, H; Zeng, J Synthesis of 5-methyl phenanthridium derivatives: a new class of human DOPA decarboxylase inhibitors. Bioorg Med Chem Lett24:2712-6 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Aromatic-L-amino-acid decarboxylase |
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| Name: | Aromatic-L-amino-acid decarboxylase |
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| Synonyms: | AADC | DDC | DDC_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53931.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_83 |
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| Residue: | 480 |
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| Sequence: | MNASEFRRRGKEMVDYMANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV
EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD
WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM
EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV
ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN
PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL
KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN
EALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE
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| BDBM25525 |
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| n/a |
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| Name | BDBM25525 |
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| Synonyms: | 24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.0^{2,10}.0^{4,8}.0^{14,22}.0^{17,21}]tetracosa-1(13),2,4(8),9,11,14(22),15,17(21),23-nonaen-24-ium | CHEMBL490129 | Pseudochelerythrine | Veadent | cid_5154 | sanguinarine | sangvinarin |
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| Type | Small organic molecule |
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| Emp. Form. | C20H14NO4 |
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| Mol. Mass. | 332.3289 |
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| SMILES | C[n+]1cc2c3OCOc3ccc2c2ccc3cc4OCOc4cc3c12 |
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| Structure | 
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