| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-glucosidase |
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| Ligand | BDBM18351 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1366789 (CHEMBL3297224) |
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| Ki | 12000±n/a nM |
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| Citation |  Zoidl, M; Müller, B; Torvisco, A; Tysoe, C; Benazza, M; Siriwardena, A; Withers, SG; Wrodnigg, TM Concise synthesis of C-1-cyano-iminosugars via a new Staudinger/aza Wittig/Strecker multicomponent reaction strategy. Bioorg Med Chem Lett24:2777-80 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-glucosidase |
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| Name: | Beta-glucosidase |
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| Synonyms: | BGLS_RHIRD | cbg-1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 88266.88 |
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| Organism: | Agrobacterium tumefaciens |
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| Description: | ChEMBL_1366789 |
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| Residue: | 818 |
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| Sequence: | MIDDILDKMTLEEQVSLLSGADFWTTVAIERLGVPKIKVTDGPNGARGGGSLVGGVKSAC
FPVAIALGATWDPELIERAGVALGGQAKSKGASVLLAPTVNIHRSGLNGRNFECYSEDPA
LTAACAVAYINGVQSQGVAATIKHFVANESEIERQTMSSDVDERTLREIYLPPFEEAVKK
AGVKAVMSSYNKLNGTYTSENPWLLTKVLREEWGFDGVVMSDWFGSHSTAETINAGLDLE
MPGPWRDRGEKLVAAVREGKVKAETVRASARRILLLLERVGAFEKAPDLAEHALDLPEDR
ALIRQLGAEGAVLLKNDGVLPLAKSSFDQIAVIGPNAASARVMGGGSARIAAHYTVSPLE
GIRAALSNANSLRHAVGCNNNRLIDVFSGEMTVEYFKGRGFESRPVHVETVEKGEFFWFD
LPSGDLDLADFSARMTATFVPQETGEHIFGMTNAGLARLFVDGELVVDGYDGWTKGENFF
GTANSEQRRAVTLGAARRYRVVVEYEAPKASLDGINICALRFGVEKPLGDAGIAEAVETA
RKSDIVLLLVGREGEWDTEGLDLPDMRLPGRQEELIEAVAETNPNVVVVLQTGGPIEMPW
LGKVRAVLQMWYPGQELGNALADVLFGDVEPAGRLPQTFPKALTDNSAITDDPSIYPGQD
GHVRYAEGIFVGYRHHDTREIEPLFPFGFGLGYTRFTWGAPQLSGTEMGADGLTVTVDVT
NIGDRAGSDVVQLYVHSPNARVERPFKELRAFAKLKLAPGATGTAVLKIAPRDLAYFDVE
AGRFRADAGKYELIVAASAIDIRASVSIHLPVDHVMEP
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| BDBM18351 |
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| n/a |
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| Name | BDBM18351 |
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| Synonyms: | (2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-triol, 10 | (2R,3R,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol | 1-Deoxynojirimycin | 1-deoxynojirimycin (DNJ) | CHEMBL307429 | US20230339856, Compound DNJ | US9181184, 1 | dNM |
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| Type | natural product |
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| Emp. Form. | C6H13NO4 |
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| Mol. Mass. | 163.1717 |
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| SMILES | OC[C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O |
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| Structure | 
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