| Reaction Details |
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 | Report a problem with these data |
| Target | Phosphorylase b kinase gamma catalytic chain, liver/testis isoform |
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| Ligand | BDBM50020310 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1365414 (CHEMBL3296773) |
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| Ki | 840±n/a nM |
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| Citation |  Zhang, L; Zheng, Q; Yang, Y; Zhou, H; Gong, X; Zhao, S; Fan, C Synthesis and in vivo SAR study of indolin-2-one-based multi-targeted inhibitors as potential anticancer agents. Eur J Med Chem82:139-51 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Phosphorylase b kinase gamma catalytic chain, liver/testis isoform |
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| Name: | Phosphorylase b kinase gamma catalytic chain, liver/testis isoform |
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| Synonyms: | PHKG2 | PHKG2_HUMAN | Phosphorylase kinase | Phosphorylase kinase gamma subunit 2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 46440.15 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_774277 |
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| Residue: | 406 |
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| Sequence: | MTLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAE
RLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLT
EKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEP
GEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQIL
MLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFFERCEGSQPW
NLTPRQRFRVAVWTVLAAGRVALSTHRVRPLTKNALLRDPYALRSVRHLIDNCAFRLYGH
WVKKGEQQNRAALFQHRPPGPFPIMGPEEEGDSAAITEDEAVLVLG
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| BDBM50020310 |
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| n/a |
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| Name | BDBM50020310 |
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| Synonyms: | CHEMBL3288854 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H28FN5O2 |
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| Mol. Mass. | 425.4991 |
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| SMILES | CN1CCN(CCC(=O)Nc2c(C)[nH]c(\C=C3/C(=O)Nc4ccc(F)cc34)c2C)CC1 |
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| Structure | 
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