| Reaction Details |
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 | Report a problem with these data |
| Target | Neuraminidase |
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| Ligand | BDBM50028521 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1437606 (CHEMBL3390208) |
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| IC50 | 11±n/a nM |
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| Citation |  Xie, Y; Xu, D; Huang, B; Ma, X; Qi, W; Shi, F; Liu, X; Zhang, Y; Xu, W Discovery of N-substituted oseltamivir derivatives as potent and selective inhibitors of H5N1 influenza neuraminidase. J Med Chem57:8445-58 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuraminidase |
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| Name: | Neuraminidase |
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| Synonyms: | n/a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 49043.64 |
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| Organism: | Influenza A virus |
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| Description: | ChEMBL_1438329 |
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| Residue: | 449 |
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| Sequence: | MNPNQKIITIGSICMVIGIVSLMLQIGNMISIWVSHSIQTGNQRQAEPISNTKFLTEKAV
ASVTLAGNSSLCPISGWAVYSKDNSIRIGSRGDVFVIREPFISCSHLECRTFFLTQGALL
NDKHSNGTVKDRSPHRTLMSCPVGEAPSPYNSRFESVAWSASACHDGTSWLTIGISGPDN
GAVAVLKYNGIITDTIKSWRNNILRTQESECACVNGSCFTVMTDGPSSGQASYKIFKMEK
GKVVKSVELDAPNYHYEECSCYPDAGEITCVCRDNWHGSNRPWVSFNQNLEYQIGYICSG
VFGDNPRPNDGTGSCGPVSPNGAYGVKGFSFKYGNGVWIGRTKSTNSRSGFEMIWDPNGW
TGTDSSFSVKQDIVAITDWSGYSGSFVQHPELTGLDCIRPCFWVELIRGRPKESTIWTSG
SSISFCGVNSDTVSWSWPDGAELPFTIDK
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| BDBM50028521 |
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| n/a |
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| Name | BDBM50028521 |
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| Synonyms: | CHEMBL3342483 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H33ClN2O4 |
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| Mol. Mass. | 485.015 |
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| SMILES | CCC(CC)O[C@@H]1C=C(C[C@H](NCc2ccc(cc2Cl)-c2ccccc2)[C@H]1NC(C)=O)C(O)=O |r,c:7| |
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| Structure | 
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