| Reaction Details |
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 | Report a problem with these data |
| Target | Bombesin receptor subtype-3 |
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| Ligand | BDBM50041424 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1445902 (CHEMBL3377329) |
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| EC50 | 5.6±n/a nM |
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| Citation |  Matsufuji, T; Shimada, K; Kobayashi, S; Ichikawa, M; Kawamura, A; Fujimoto, T; Arita, T; Hara, T; Konishi, M; Abe-Ohya, R; Izumi, M; Sogawa, Y; Nagai, Y; Yoshida, K; Abe, Y; Kimura, T; Takahashi, H Synthesis and biological evaluation of novel chiral diazepine derivatives as bombesin receptor subtype-3 (BRS-3) agonists incorporating an antedrug approach. Bioorg Med Chem23:89-104 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Bombesin receptor subtype-3 |
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| Name: | Bombesin receptor subtype-3 |
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| Synonyms: | BRS3_MOUSE | Brs3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44239.49 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1445902 |
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| Residue: | 399 |
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| Sequence: | MSQRQSQSPNQTLISITNDTETSSSVVSNDTTHKGWTGDNSPGIEALCAIYITYAGIISV
GILGNAILIKVFFKTKSMQTVPNIFITSLAFGDLLLLLTCVPVDATHYLAEGWLFGKVGC
KVLSFIRLTSVGVSVFTLTILSADRYKAVVKPLERQPPNAILKTCAKAGGIWIVSMIFAL
PEAIFSNVYTFQDPNRNVTFESCNSYPISERLLQEIHSLLCFLVFYIIPLSIISVYYSLI
ARTLYKSTLNIPTEEQSHARKQIESRKRIAKTVLVLVALFALCWLPNHLLYLYHSFTYES
YANHSDVPFVIIIFSRVLAFSNSCVNPFALYWLSKTFQQHFKAQLCCLKAEQPEPPLGDI
PLNNLTVMGRVPATGSAHVSEISVTLFSGSSAKKGEDKV
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| BDBM50041424 |
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| n/a |
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| Name | BDBM50041424 |
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| Synonyms: | CHEMBL3356411 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H26F3N3O5 |
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| Mol. Mass. | 493.4755 |
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| SMILES | CCCCOC(=O)c1cccc(CC(=O)N2CCNc3nc(ccc3[C@H]2CC(O)=O)C(F)(F)F)c1 |r| |
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| Structure | 
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