| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 5 (neutral amino acid transporters, system A), member 4b |
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| Ligand | BDBM50044849 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1456196 (CHEMBL3361951) |
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| IC50 | <39811±n/a nM |
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| Citation |  Sparks, SM; Chen, G; Collins, JL; Danger, D; Dock, ST; Jayawickreme, C; Jenkinson, S; Laudeman, C; Leesnitzer, MA; Liang, X; Maloney, P; McCoy, DC; Moncol, D; Rash, V; Rimele, T; Vulimiri, P; Way, JM; Ross, S Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120). Bioorg Med Chem Lett24:3100-3 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier family 5 (neutral amino acid transporters, system A), member 4b |
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| Name: | Solute carrier family 5 (neutral amino acid transporters, system A), member 4b |
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| Synonyms: | MCG3105, isoform CRA_a | Protein Slc5a4b | SGLT3-b | Slc5a4b |
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| Type: | PROTEIN |
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| Mol. Mass.: | 72244.70 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_109433 |
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| Residue: | 660 |
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| Sequence: | MASTLSPSITPQTEEPPVVPVRIQNAADISVIVIYFIVVLAVGLWSMVRSNRGTVGGFFL
AGHDMAWWPMGASLFASNIGSNHFVGLAGTGAASGIAIAAVEWNALLMVLVLGWVFLPIY
IKAGVLTMPEYLRKRFGGKRLQIYLSVLSLFIMVALQTSSIIFSGAIFIQLALGLNLYLA
VFILLAITAFYTVAGGLASVIYTDSVQTFIMLLGSLILMGFAFAEVGGYESFTEKYMNAI
PSVVEGDNLTISPKCYTPQPDSFHVFRDPVTGDIPWPGLIFGMTILAIWYWCADQVIVQR
CLCGKNMSHVKAACILCGYLKLLPMFLMVMPGMISRILYTDKVACVVPSECEKQCGTAVG
CTNYAYPTLVLELMPDGLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLYTKIRKKASER
ELMIAGRIFGMVLIAVSILWVPLVQVSQNGQLFHYIGSVSSYLGPPLGAVFMLAIFFKRV
NEQGAFWGLMVGLVVGLIRLIAEFVYGTGSCVAPSNCPKIICGVHYMYFAIILFFVSIIV
ILGVSFLTEPIPDVHLYRLCWSLWNNTEERIDLDAEELETQEEAGGALEEDSEQSRGCLK
RACCLLCGLQNTGPKLTKEEEAALRQKFSDTSEKPLWRTVMNINAVLLLGVAVFVHAYFA
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| BDBM50044849 |
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| n/a |
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| Name | BDBM50044849 |
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| Synonyms: | CHEMBL3311308 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H19NO3S |
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| Mol. Mass. | 305.392 |
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| SMILES | COc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(C)cc1C |
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| Structure | 
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