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TargetSuccinate-semialdehyde dehydrogenase, mitochondrial
LigandBDBM23411
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1459249 (CHEMBL3367479)
IC50 7200000±n/a nM
Citation Singh, M; Kaur, M; Silakari, O Flavones: an important scaffold for medicinal chemistry. Eur J Med Chem84:206-39 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Succinate-semialdehyde dehydrogenase, mitochondrial
Name:Succinate-semialdehyde dehydrogenase, mitochondrial
Synonyms:ALDH5A1 | Aldehyde dehydrogenase family 5 member A1 | NAD(+)-dependent succinic semialdehyde dehydrogenase | SSADH | SSDH_HUMAN | Succinate semialdehyde dehydrogenase | Succinate-semialdehyde dehydrogenase, mitochondrial
Type:PROTEIN
Mol. Mass.:57224.70
Organism:Homo sapiens (Human)
Description:ChEMBL_1459249
Residue:535
Sequence:
MATCIWLRSCGARRLGSTFPGCRLRPRAGGLVPASGPAPGPAQLRCYAGRLAGLSAALLR
TDSFVGGRWLPAAATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCRWREVSAKER
SSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVYGDIIH
TPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALAL
AELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHAANSV
KRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHDAFVKAF
AEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQLGKNFF
EPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQDPAQIWR
VAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYVCYGGL
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  Blast E-value cutoff:
BDBM23411
n/a
NameBDBM23411
Synonyms:5,6,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one | Scutel-larei | Scutellarein | Scutellarein (2) | Scutellarein (28) | US10252984, Table 2.2
Typeflavone
Emp. Form.C15H10O6
Mol. Mass.286.2363
SMILESOc1ccc(cc1)-c1cc(=O)c2c(O)c(O)c(O)cc2o1
Structure
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