| Reaction Details |
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 | Report a problem with these data |
| Target | Somatostatin receptor type 3 |
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| Ligand | BDBM50053739 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1447893 (CHEMBL3378640) |
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| IC50 | 0.520000±n/a nM |
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| Citation |  He, S; Lai, Z; Ye, Z; Dobbelaar, PH; Shah, SK; Truong, Q; Du, W; Guo, L; Liu, J; Jian, T; Qi, H; Bakshi, RK; Hong, Q; Dellureficio, J; Reibarkh, M; Samuel, K; Reddy, VB; Mitelman, S; Tong, SX; Chicchi, GG; Tsao, KL; Trusca, D; Wu, M; Shao, Q; Trujillo, ME; Fernandez, G; Nelson, D; Bunting, P; Kerr, J; Fitzgerald, P; Morissette, P; Volksdorf, S; Eiermann, GJ; Li, C; Zhang, B; Howard, AD; Zhou, YP; Nargund, RP; Hagmann, WK Investigation of Cardiovascular Effects of Tetrahydro-ß-carboline sstr3 antagonists. ACS Med Chem Lett5:748-53 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Somatostatin receptor type 3 |
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| Name: | Somatostatin receptor type 3 |
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| Synonyms: | SOMATOSTATIN SST3 | SS-3-R | SS3-R | SS3R | SSR-28 | SSR3_HUMAN | SSTR3 | Somatostatin receptor type 3 (SSTR3) |
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| Type: | Protein |
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| Mol. Mass.: | 45855.97 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P32745 |
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| Residue: | 418 |
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| Sequence: | MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLL
GNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVM
AVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVV
FSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRV
WAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVA
LPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEE
SREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL
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| BDBM50053739 |
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| n/a |
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| Name | BDBM50053739 |
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| Synonyms: | CHEMBL3323084 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H24FN7O2 |
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| Mol. Mass. | 533.5557 |
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| SMILES | Cn1cc(cn1)[C@]1(N[C@H](Cc2c1[nH]c1ccccc21)c1nc(c[nH]1)-c1ccc(F)cc1)c1cncc(c1)C(O)=O |r| |
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| Structure | 
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