| Reaction Details |
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 | Report a problem with these data |
| Target | Mannose-6-phosphate isomerase |
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| Ligand | BDBM46038 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1448919 (CHEMBL3375686) |
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| IC50 | 23000±n/a nM |
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| Citation |  Bravo, Y; Teriete, P; Dhanya, RP; Dahl, R; Lee, PS; Kiffer-Moreira, T; Ganji, SR; Sergienko, E; Smith, LH; Farquharson, C; Millán, JL; Cosford, ND Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1. Bioorg Med Chem Lett24:4308-11 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mannose-6-phosphate isomerase |
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| Name: | Mannose-6-phosphate isomerase |
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| Synonyms: | MPI | MPI protein | MPI_HUMAN | Mannose-6-phosphate isomerase | PMI1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 46651.35 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1448919 |
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| Residue: | 423 |
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| Sequence: | MAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAK
ILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEK
LHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLK
QTMSHDSQAVASSLQSCFSHLMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQ
LHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTP
KFIDVPTLCEMLSYTPSSSKDRLFLPTRSQEDPYLSIYDPPVPDFTIMKTEVPGSVTEYK
VLALDSASILLMVQGTVIASTPTTQTPIPLQRGGVLFIGANESVSLKLTEPKDLLIFRAC
CLL
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| BDBM46038 |
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| n/a |
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| Name | BDBM46038 |
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| Synonyms: | 4-(3-keto-1,2-benzothiazol-2-yl)benzoic acid ethyl ester | 4-(3-oxo-1,2-benzothiazol-2-yl)benzoic acid ethyl ester | MLS-0315808.0001 | cid_2467794 | ethyl 4-(3-oxidanylidene-1,2-benzothiazol-2-yl)benzoate | ethyl 4-(3-oxo-1,2-benzothiazol-2-yl)benzoate |
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| Type | Small organic molecule |
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| Emp. Form. | C16H13NO3S |
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| Mol. Mass. | 299.344 |
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| SMILES | CCOC(=O)c1ccc(cc1)-n1sc2ccccc2c1=O |
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| Structure | 
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