| Reaction Details |
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 | Report a problem with these data |
| Target | Glucagon receptor |
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| Ligand | BDBM50057824 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1450588 (CHEMBL3372166) |
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| IC50 | 87±n/a nM |
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| Citation |  Hasegawa, F; Niidome, K; Migihashi, C; Murata, M; Negoro, T; Matsumoto, T; Kato, K; Fujii, A Discovery of furan-2-carbohydrazides as orally active glucagon receptor antagonists. Bioorg Med Chem Lett24:4266-70 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glucagon receptor |
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| Name: | Glucagon receptor |
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| Synonyms: | GL-R | GLR_RAT | Gcgr |
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| Type: | PROTEIN |
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| Mol. Mass.: | 55053.40 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1450588 |
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| Residue: | 485 |
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| Sequence: | MLLTQLHCPYLLLLLVVLSCLPKAPSAQVMDFLFEKWKLYSDQCHHNLSLLPPPTELVCN
RTFDKYSCWPDTPPNTTANISCPWYLPWYHKVQHRLVFKRCGPDGQWVRGPRGQSWRDAS
QCQMDDDEIEVQKGVAKMYSSYQVMYTVGYSLSLGALLLALVILLGLRKLHCTRNYIHGN
LFASFVLKAGSVLVIDWLLKTRYSQKIGDDLSVSVWLSDGAVAGCRVATVIMQYGIIANY
CWLLVEGVYLYSLLSITTFSEKSFFSLYLCIGWGSPLLFVIPWVVVKCLFENVQCWTSND
NMGFWWILRIPVLLAILINFFIFVRIIHLLVAKLRAHQMHYADYKFRLARSTLTLIPLLG
VHEVVFAFVTDEHAQGTLRSTKLFFDLFFSSFQGLLVAVLYCFLNKEVQAELLRRWRRWQ
EGKALQEERMASSHGSHMAPAGTCHGDPCEKLQLMSAGSSSGTGCEPSAKTSLASSLPRL
ADSPT
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| BDBM50057824 |
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| n/a |
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| Name | BDBM50057824 |
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| Synonyms: | CHEMBL3326175 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H17N3O6 |
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| Mol. Mass. | 443.4083 |
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| SMILES | Oc1ccc(cc1[N+]([O-])=O)C(=O)NNC(=O)c1occ(c1-c1ccccc1)-c1ccccc1 |
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| Structure | 
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