Reaction Details |
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Target | Macrophage migration inhibitory factor |
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Ligand | BDBM50073659 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1467648 (CHEMBL3411010) |
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IC50 | 29000±n/a nM |
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Citation | Spencer, ES; Dale, EJ; Gommans, AL; Rutledge, MT; Vo, CT; Nakatani, Y; Gamble, AB; Smith, RA; Wilbanks, SM; Hampton, MB; Tyndall, JD Multiple binding modes of isothiocyanates that inhibit macrophage migration inhibitory factor. Eur J Med Chem93:501-10 (2015) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Macrophage migration inhibitory factor |
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Name: | Macrophage migration inhibitory factor |
Synonyms: | GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase |
Type: | Enzyme |
Mol. Mass.: | 12478.18 |
Organism: | Homo sapiens (Human) |
Description: | P14174 |
Residue: | 115 |
Sequence: | MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALC
SLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
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BDBM50073659 |
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n/a |
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Name | BDBM50073659 |
Synonyms: | CHEMBL3409220 |
Type | Small organic molecule |
Emp. Form. | C9H9NO2S |
Mol. Mass. | 195.238 |
SMILES | Oc1ccc(CCN=C=S)cc1O |
Structure |
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