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TargetMacrophage migration inhibitory factor
LigandBDBM50073717
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1467649 (CHEMBL3411011)
IC50>100000±n/a nM
Citation Spencer, ESDale, EJGommans, ALRutledge, MTVo, CTNakatani, YGamble, ABSmith, RAWilbanks, SMHampton, MBTyndall, JD Multiple binding modes of isothiocyanates that inhibit macrophage migration inhibitory factor. Eur J Med Chem93:501-10 (2015) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Macrophage migration inhibitory factor
Name:Macrophage migration inhibitory factor
Synonyms:GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase
Type:Enzyme
Mol. Mass.:12478.18
Organism:Homo sapiens (Human)
Description:P14174
Residue:115
Sequence:
MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALC
SLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50073717
n/a
NameBDBM50073717
Synonyms:CHEMBL3409412
TypeSmall organic molecule
Emp. Form.C14H11NS
Mol. Mass.225.309
SMILESS=C=NC(c1ccccc1)c1ccccc1
Structure
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