| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Coagulation factor XIII |
|---|
| Ligand | BDBM50009248 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1475035 |
|---|
| IC50 | 4000±n/a nM |
|---|
| Citation |  Avery CA; Pease RJ; Smith K; Boothby M; Buckley HM; Grant PJ; Fishwick CW (±) cis-Bisamido epoxides: A novel series of potent FXIII-A inhibitors. Eur J Med Chem 98:49-53 (2015) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Coagulation factor XIII |
|---|
| Name: | Coagulation factor XIII |
|---|
| Synonyms: | n/a |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 83261.29 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1475048 |
|---|
| Residue: | 732 |
|---|
| Sequence: | MSETSRTAFGGRRAVPPNNSNAAEDDLPTVELQGVVPRGVNLQEFLNVTSVHLFKERWDT
NKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYVIGRYPQENKGTYIPV
PIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNPETD
TYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILDTCL
YVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSVDIL
LEYRSSENPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFLEEDGN
VNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAIKH
GHVCFQFDAPFVFAEVNSDLIYITAKKDGTHVVENVDATHIGKLIVTKQIGGDGMMDITD
TYKFQEGQEEERLALETALMYGAKKPLNTEGVMKSRSNVDMDFEVENAVLGKDFKLSITF
RNNSHNRYTITAYLSANITFYTGVPKAEFKKETFDVTLEPLSFKKEAVLIQAGEYMGQLL
EQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVGSDMTVTVQFTNPLKET
LRNVWVHLDGPGVTRPMKKMFREIRPNSTVQWEEVCRPWVSGHRKLIASMSSDSLRHVYG
ELDVQIQRRPSM
|
|
|
|---|
| BDBM50009248 |
|---|
| n/a |
|---|
| Name | BDBM50009248 |
|---|
| Synonyms: | (2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-carboxylic acid amide | (2R,3S)-3-((4E,7E)-nona-4,7-dienoyl)oxirane-2-carboxamide | 3-Nona-4,7-dienoyl-oxirane-2-carboxylic acid amide | 3-Nona-4,7-dienoyl-oxirane-2-carboxylic acid amide(Cerulenin) | CERULENIN | CHEMBL45627 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H17NO3 |
|---|
| Mol. Mass. | 223.2683 |
|---|
| SMILES | C\C=C\C\C=C\CCC(=O)[C@H]1O[C@H]1C(N)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
