| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Tyrosine-protein phosphatase non-receptor type 3 |
|---|
| Ligand | BDBM50087856 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1476060 (CHEMBL3428556) |
|---|
| pH | 7±n/a |
|---|
| IC50 | 13900±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  He, Y; Guo, X; Yu, ZH; Wu, L; Gunawan, AM; Zhang, Y; Dixon, JE; Zhang, ZY A potent and selective inhibitor for the UBLCP1 proteasome phosphatase. Bioorg Med Chem23:2798-809 (2015) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Tyrosine-protein phosphatase non-receptor type 3 |
|---|
| Name: | Tyrosine-protein phosphatase non-receptor type 3 |
|---|
| Synonyms: | PTN3_HUMAN | PTP-H1 | PTPH1 | PTPN3 | Protein-tyrosine phosphatase H1 | Protein-tyrosine phosphatase H1 (PTPH1) | Tyrosine-protein phosphatase non-receptor type 3 | Tyrosine-protein phosphatase non-receptor type 3 (PTPH1) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 103998.76 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P26045 |
|---|
| Residue: | 913 |
|---|
| Sequence: | MTSRLRALGGRINNIRTSELPKEKTRSEVICSIHFLDGVVQTFKVTKQDTGQVLLDMVHN
HLGVTEKEYFGLQHDDDSVDSPRWLEASKAIRKQLKGGFPCTLHFRVRFFIPDPNTLQQE
QTRHLYFLQLKMDICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQ
NEDFLTKVESLHEQHSGLKQSEAESCYINIARTLDFYGVELHSGRDLHNLDLMIGIASAG
VAVYRKYICTSFYPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKS
CVEHHTFFQAKKLLPQEKNVLSQYWTMGSRNTKKSVNNQYCKKVIGGMVWNPAMRRSLSV
EHLETKSLPSRSPPITPNWRSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGSL
APQDSDSEVSQNRSPHQESLSENNPAQSYLTQKSSSSVSPSSNAPGSCSPDGVDQQLLDD
FHRVTKGGSTEDASQYYCDKNDNGDSYLVLIRITPDEDGKFGFNLKGGVDQKMPLVVSRI
NPESPADTCIPKLNEGDQIVLINGRDISEHTHDQVVMFIKASRESHSRELALVIRRRAVR
SFADFKSEDELNQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGL
AITFAKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGP
LPHTCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDCT
IAYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLV
HCSAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILR
VYEEGLVQMLDPS
|
|
|
|---|
| BDBM50087856 |
|---|
| n/a |
|---|
| Name | BDBM50087856 |
|---|
| Synonyms: | CHEMBL3426913 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C28H30F3NO6 |
|---|
| Mol. Mass. | 533.5361 |
|---|
| SMILES | CCCCC(Oc1cc(O)c(cc1C#Cc1ccccc1OC(F)(F)F)C(O)=O)C(=O)NC1CCCCC1 |
|---|
| Structure | 
|
|---|
Search and Browse
