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TargetEquilibrative nucleoside transporter 1
LigandBDBM50088517
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1494513 (CHEMBL3528990)
Ki 51000±n/a nM
Citation Lepist, EI; Damaraju, VL; Zhang, J; Gati, WP; Yao, SY; Smith, KM; Karpinski, E; Young, JD; Leung, KH; Cass, CE Transport of A1 adenosine receptor agonist tecadenoson by human and mouse nucleoside transporters: evidence for blood-brain barrier transport by murine equilibrative nucleoside transporter 1 mENT1. Drug Metab Dispos41:916-22 (2013) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Equilibrative nucleoside transporter 1
Name:Equilibrative nucleoside transporter 1
Synonyms:ENT1 | Equilibrative NBMPR-sensitive nucleoside transporter | Equilibrative Nucleoside Transporter 1 (ENT1) | Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter | Equilibrative nucleoside transporter 1 | Nucleoside transporter, es-type | S29A1_HUMAN | SLC29A1 | Solute carrier family 29 member 1
Type:Multi-pass membrane protein
Mol. Mass.:50225.92
Organism:Homo sapiens (Human)
Description:n/a
Residue:456
Sequence:
MTTSHQPQDRYKAVWLIFFMLGLGTLLPWNFFMTATQYFTNRLDMSQNVSLVTAELSKDA
QASAAPAAPLPERNSLSAIFNNVMTLCAMLPLLLFTYLNSFLHQRIPQSVRILGSLVAIL
LVFLITAILVKVQLDALPFFVITMIKIVLINSFGAILQGSLFGLAGLLPASYTAPIMSGQ
GLAGFFASVAMICAIASGSELSESAFGYFITACAVIILTIICYLGLPRLEFYRYYQQLKL
EGPGEQETKLDLISKGEEPRAGKEESGVSVSNSQPTNESHSIKAILKNISVLAFSVCFIF
TITIGMFPAVTVEVKSSIAGSSTWERYFIPVSCFLTFNIFDWLGRSLTAVFMWPGKDSRW
LPSLVLARLVFVPLLLLCNIKPRRYLTVVFEHDAWFIFFMAAFAFSNGYLASLCMCFGPK
KVKPAEAETAGAIMAFFLCLGLALGAVFSFLFRAIV
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50088517
n/a
NameBDBM50088517
Synonyms:CHEBI:16704 | Uridine
TypeSmall organic molecule
Emp. Form.C9H12N2O6
Mol. Mass.244.2014
SMILESOC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O |r|
Structure
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