| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase |
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| Ligand | BDBM50090510 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1498284 (CHEMBL3583805) |
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| IC50 | >30000±n/a nM |
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| Citation |  Sato, K; Takahagi, H; Yoshikawa, T; Morimoto, S; Takai, T; Hidaka, K; Kamaura, M; Kubo, O; Adachi, R; Ishii, T; Maki, T; Mochida, T; Takekawa, S; Nakakariya, M; Amano, N; Kitazaki, T Discovery of a Novel Series of N-Phenylindoline-5-sulfonamide Derivatives as Potent, Selective, and Orally Bioavailable Acyl CoA:Monoacylglycerol Acyltransferase-2 Inhibitors. J Med Chem58:3892-909 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase |
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| Name: | Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase |
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| Synonyms: | GGNT3 | GNT-III | GlcNAc-T III | MGAT3 | MGAT3_HUMAN | N-acetylglucosaminyltransferase III | N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III |
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| Type: | PROTEIN |
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| Mol. Mass.: | 61324.81 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_107586 |
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| Residue: | 533 |
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| Sequence: | MKMRRYKLFLMFCMAGLCLISFLHFFKTLSYVTFPRELASLSPNLVSSFFWNNAPVTPQA
SPEPGGPDLLRTPLYSHSPLLQPLPPSKAAEELHRVDLVLPEDTTEYFVRTKAGGVCFKP
GTKMLERPPPGRPEEKPEGANGSSARRPPRYLLSARERTGGRGARRKWVECVCLPGWHGP
SCGVPTVVQYSNLPTKERLVPREVPRRVINAINVNHEFDLLDVRFHELGDVVDAFVVCES
NFTAYGEPRPLKFREMLTNGTFEYIRHKVLYVFLDHFPPGGRQDGWIADDYLRTFLTQDG
VSRLRNLRPDDVFIIDDADEIPARDGVLFLKLYDGWTEPFAFHMRKSLYGFFWKQPGTLE
VVSGCTVDMLQAVYGLDGIRLRRRQYYTMPNFRQYENRTGHILVQWSLGSPLHFAGWHCS
WCFTPEGIYFKLVSAQNGDFPRWGDYEDKRDLNYIRGLIRTGGWFDGTQQEYPPADPSEH
MYAPKYLLKNYDRFHYLLDNPYQEPRSTAAGGWRHRGPEGRPPARGKLDEAEV
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| BDBM50090510 |
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| n/a |
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| Name | BDBM50090510 |
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| Synonyms: | CHEMBL3581716 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H23F2N3O3S |
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| Mol. Mass. | 471.52 |
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| SMILES | CC(=O)Nc1cc(cc2CCN(CCc3ccccc3)c12)S(=O)(=O)Nc1ccc(F)cc1F |
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| Structure | 
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