| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Glyceraldehyde-3-phosphate dehydrogenase |
|---|
| Ligand | BDBM50114358 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1511315 (CHEMBL3606220) |
|---|
| IC50 | 1410±n/a nM |
|---|
| Citation |  Prati, F; Bergamini, C; Molina, MT; Falchi, F; Cavalli, A; Kaiser, M; Brun, R; Fato, R; Bolognesi, ML 2-Phenoxy-1,4-naphthoquinones: From a Multitarget Antitrypanosomal to a Potential Antitumor Profile. J Med Chem58:6422-34 (2015) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Glyceraldehyde-3-phosphate dehydrogenase |
|---|
| Name: | Glyceraldehyde-3-phosphate dehydrogenase |
|---|
| Synonyms: | G3P_HUMAN | GAPD | GAPDH | Glyceraldehyde-3-phosphate dehydrogenase liver |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 36060.86 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1511315 |
|---|
| Residue: | 335 |
|---|
| Sequence: | MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTV
KAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVI
ISAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHA
ITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANV
SVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAG
IALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE
|
|
|
|---|
| BDBM50114358 |
|---|
| n/a |
|---|
| Name | BDBM50114358 |
|---|
| Synonyms: | CHEMBL3604098 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H14O4 |
|---|
| Mol. Mass. | 330.3335 |
|---|
| SMILES | COc1ccc(OC2=CC(=O)c3cc4ccccc4cc3C2=O)cc1 |t:7| |
|---|
| Structure | 
|
|---|
Search and Browse
