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TargetPurine Nucleoside Phosphorylase (PNP)
LigandBDBM50116358
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1511507
Ki 93±n/a nM
Citation Evans GBCameron SALuxenburger AGuan RSuarez JThomas KSchramm VLTyler PC Tight binding enantiomers of pre-clinical drug candidates. Bioorg Med Chem 23:5326-33 (2015) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Purine Nucleoside Phosphorylase (PNP)
Name:Purine Nucleoside Phosphorylase (PNP)
Synonyms:pfPNP
Type:Enzyme
Mol. Mass.:26857.85
Organism:Plasmodium falciparum
Description:n/a
Residue:245
Sequence:
MDNLLRHLKISKEQITPVVLVVGDPGRVDKIKVVCDSYVDLAYNREYKSVECHYKGQKFL
CVSHGVGSAGCAVCFEELCQNGAKVIIRAGSCGSLQPDLIKRGDICICNAAVREDRVSHL
LIHGDFPAVGDFDVYDTLNKCAQELNVPVFNGISVSSDMYYPNKIIPSRLEDYSKANAAV
VEMELATLMVIGTLRKVKTGGILIVDGCPFKWDEGDFDNNLVPHQLENMIKIALGACAKL
ATKYA
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  Blast E-value cutoff:
BDBM50116358
n/a
NameBDBM50116358
Synonyms:CHEMBL3604359
TypeSmall organic molecule
Emp. Form.C13H18N4O2S
Mol. Mass.294.373
SMILESCSC[C@@H]1CN(Cc2c[nH]c3c(O)ncnc23)C[C@H]1O |r|
Structure
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