| Reaction Details |
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 | Report a problem with these data |
| Target | D-aspartate oxidase |
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| Ligand | BDBM14673 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1517182 (CHEMBL3620072) |
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| Ki | 153000±n/a nM |
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| Citation |  Katane, M; Yamada, S; Kawaguchi, G; Chinen, M; Matsumura, M; Ando, T; Doi, I; Nakayama, K; Kaneko, Y; Matsuda, S; Saitoh, Y; Miyamoto, T; Sekine, M; Yamaotsu, N; Hirono, S; Homma, H Identification of Novel D-Aspartate Oxidase Inhibitors by in Silico Screening and Their Functional and Structural Characterization in Vitro. J Med Chem58:7328-40 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D-aspartate oxidase |
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| Name: | D-aspartate oxidase |
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| Synonyms: | D-Aspartate Oxidase (DDO) | DASOX | DDO | OXDD_HUMAN |
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| Type: | Oxidoreductase |
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| Mol. Mass.: | 37543.06 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Recombinant human DDO expressed and purified from sf9 insect cells, was used in enzyme assays. |
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| Residue: | 341 |
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| Sequence: | MDTARIAVVGAGVVGLSTAVCISKLVPRCSVTIISDKFTPDTTSDVAAGMLIPHTYPDTP
IHTQKQWFRETFNHLFAIANSAEAGDAGVHLVSGWQIFQSTPTEEVPFWADVVLGFRKMT
EAELKKFPQYVFGQAFTTLKCECPAYLPWLEKRIKGSGGWTLTRRIEDLWELHPSFDIVV
NCSGLGSRQLAGDSKIFPVRGQVLQVQAPWVEHFIRDGSGLTYIYPGTSHVTLGGTRQKG
DWNLSPDAENSREILSRCCALEPSLHGACNIREKVGLRPYRPGVRLQTELLARDGQRLPV
VHHYGHGSGGISVHWGTALEAARLVSECVHALRTPIPKSNL
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| BDBM14673 |
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| n/a |
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| Name | BDBM14673 |
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| Synonyms: | Fragment 3 | Malonic Acid | propanedioic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C3H4O4 |
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| Mol. Mass. | 104.0615 |
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| SMILES | OC(=O)CC(O)=O |
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| Structure | 
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