| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D-amino-acid oxidase |
|---|
| Ligand | BDBM23515 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1517180 (CHEMBL3620070) |
|---|
| IC50 | 1125000±n/a nM |
|---|
| Citation |  Katane, M; Yamada, S; Kawaguchi, G; Chinen, M; Matsumura, M; Ando, T; Doi, I; Nakayama, K; Kaneko, Y; Matsuda, S; Saitoh, Y; Miyamoto, T; Sekine, M; Yamaotsu, N; Hirono, S; Homma, H Identification of Novel D-Aspartate Oxidase Inhibitors by in Silico Screening and Their Functional and Structural Characterization in Vitro. J Med Chem58:7328-40 (2015) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D-amino-acid oxidase |
|---|
| Name: | D-amino-acid oxidase |
|---|
| Synonyms: | D-amino-acid oxidase (DAAO) | DAAO | DAMOX | DAO | OXDA_HUMAN |
|---|
| Type: | Homodimer |
|---|
| Mol. Mass.: | 39476.06 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P14920 |
|---|
| Residue: | 347 |
|---|
| Sequence: | MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAGLWQPYLSDPN
NPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFRKLTPR
ELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEEVAREGADVIVN
CTGVWAGALQRDPLLQPGRGQIMKVDAPWMKHFILTHDPERGIYNSPYIIPGTQTVTLGG
IFQLGNWSELNNIQDHNTIWEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGP
SNTEVIHNYGHGGYGLTIHWGCALEAAKLFGRILEEKKLSRMPPSHL
|
|
|
|---|
| BDBM23515 |
|---|
| n/a |
|---|
| Name | BDBM23515 |
|---|
| Synonyms: | CHEMBL573 | Niacin | Nicotinic Acid | [5, 6-3H]-niacin | pyridine-3-carboxylic acid | wampocap |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C6H5NO2 |
|---|
| Mol. Mass. | 123.1094 |
|---|
| SMILES | OC(=O)c1cccnc1 |
|---|
| Structure | 
|
|---|
Search and Browse
