| Reaction Details |
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 | Report a problem with these data |
| Target | Probable G-protein coupled receptor 139 |
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| Ligand | BDBM50131994 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1526933 (CHEMBL3637279) |
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| EC50 | 52±n/a nM |
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| Citation |  Dvorak, CA; Coate, H; Nepomuceno, D; Wennerholm, M; Kuei, C; Lord, B; Woody, D; Bonaventure, P; Liu, C; Lovenberg, T; Carruthers, NI Identification and SAR of Glycine Benzamides as Potent Agonists for the GPR139 Receptor. ACS Med Chem Lett6:1015-8 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Probable G-protein coupled receptor 139 |
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| Name: | Probable G-protein coupled receptor 139 |
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| Synonyms: | G(q)-coupled orphan receptor GPRg1 | G-protein coupled receptor 139 | G-protein-coupled receptor PGR3 | GP139_HUMAN | GPR139 | GPRG1 | GPRG1 | PGR3 | Probable G-protein coupled receptor 139 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40700.34 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_109920 |
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| Residue: | 353 |
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| Sequence: | MEHTHAHLAANSSLSWWSPGSACGLGFVPVVYYSLLLCLGLPANILTVIILSQLVARRQK
SSYNYLLALAAADILVLFFIVFVDFLLEDFILNMQMPQVPDKIIEVLEFSSIHTSIWITV
PLTIDRYIAVCHPLKYHTVSYPARTRKVIVSVYITCFLTSIPYYWWPNIWTEDYISTSVH
HVLIWIHCFTVYLVPCSIFFILNSIIVYKLRRKSNFRLRGYSTGKTTAILFTITSIFATL
WAPRIIMILYHLYGAPIQNRWLVHIMSDIANMLALLNTAINFFLYCFISKRFRTMAAATL
KAFFKCQKQPVQFYTNHNFSITSSPWISPANSHCIKMLVYQYDKNGKPIKVSP
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| BDBM50131994 |
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| n/a |
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| Name | BDBM50131994 |
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| Synonyms: | CHEMBL3633882 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H17F3N2O2 |
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| Mol. Mass. | 350.335 |
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| SMILES | C[C@H](NC(=O)CNC(=O)c1cccc(c1)C(F)(F)F)c1ccccc1 |r| |
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| Structure | 
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