Reaction Details |
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Target | Protein S100-B |
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Ligand | BDBM50146592 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1555503 (CHEMBL3768085) |
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IC50 | 18300±n/a nM |
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Citation | Cavalier, MC; Ansari, MI; Pierce, AD; Wilder, PT; McKnight, LE; Raman, EP; Neau, DB; Bezawada, P; Alasady, MJ; Charpentier, TH; Varney, KM; Toth, EA; MacKerell, AD; Coop, A; Weber, DJ Small Molecule Inhibitors of Ca(2+)-S100B Reveal Two Protein Conformations. J Med Chem59:592-608 (2016) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Protein S100-B |
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Name: | Protein S100-B |
Synonyms: | Protein S100-B | S-100 protein beta chain | S-100 protein subunit beta | S100 calcium-binding protein B | S100B_RAT | S100b |
Type: | PROTEIN |
Mol. Mass.: | 10731.34 |
Organism: | Rattus norvegicus |
Description: | ChEMBL_116732 |
Residue: | 92 |
Sequence: | MSELEKAMVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMET
LDEDGDGECDFQEFMAFVSMVTTACHEFFEHE
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BDBM50146592 |
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n/a |
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Name | BDBM50146592 |
Synonyms: | CHEMBL3764285 |
Type | Small organic molecule |
Emp. Form. | C36H60N6O2 |
Mol. Mass. | 608.9006 |
SMILES | NCCCCCCCNC(=N)c1ccc(OCCCCCCCCOc2ccc(cc2)C(=N)NCCCCCCCN)cc1 |
Structure |
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