| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cathepsin K |
|---|
| Ligand | BDBM50168938 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_1577556 |
|---|
| Ki | 930±n/a nM |
|---|
| Citation |  Schmitz, J; Li, T; Bartz, U; Gütschow, M Cathepsin B Inhibitors: Combining Dipeptide Nitriles with an Occluding Loop Recognition Element by Click Chemistry. ACS Med Chem Lett7:211-6 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cathepsin K |
|---|
| Name: | Cathepsin K |
|---|
| Synonyms: | CATK_HUMAN | CTSK | CTSO | CTSO2 | Cathepsin O | Cathepsin O2 | Cathepsin X |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 36975.68 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P43235 |
|---|
| Residue: | 329 |
|---|
| Sequence: | MWGLKVLLLPVVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIH
NLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVD
YRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGG
YMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVA
RVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGE
NWGNKGYILMARNKNNACGIANLASFPKM
|
|
|
|---|
| BDBM50168938 |
|---|
| n/a |
|---|
| Name | BDBM50168938 |
|---|
| Synonyms: | CHEMBL3805662 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H20BrN3O2 |
|---|
| Mol. Mass. | 462.339 |
|---|
| SMILES | Brc1cccc(C[C@H](NC(=O)c2ccc(cc2)-c2ccccc2)C(=O)NCC#N)c1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
