| Reaction Details |
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 | Report a problem with these data |
| Target | Lysophosphatidic acid receptor 2 |
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| Ligand | BDBM50195700 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1617902 (CHEMBL3859971) |
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| IC50 | 790±n/a nM |
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| Citation |  Terakado, M; Suzuki, H; Hashimura, K; Tanaka, M; Ueda, H; Kohno, H; Fujimoto, T; Saga, H; Nakade, S; Habashita, H; Takaoka, Y; Seko, T Discovery of ONO-7300243 from a Novel Class of Lysophosphatidic Acid Receptor 1 Antagonists: From Hit to Lead. ACS Med Chem Lett7:913-918 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Lysophosphatidic acid receptor 2 |
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| Name: | Lysophosphatidic acid receptor 2 |
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| Synonyms: | EDG4 | LPA receptor 2 | LPA-2 | LPA2 | LPAR2 | LPAR2_HUMAN | Lysophosphatidic acid receptor 2 | Lysophosphatidic acid receptor Edg-4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 39103.44 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1451385 |
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| Residue: | 351 |
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| Sequence: | MVIMGQCYYNETIGFFYNNSGKELSSHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASN
RRFHQPIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVA
TLLAIAVERHRSVMAVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSR
MAPLLSRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLV
KTVVIILGAFVVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDA
EMRRTFRRLLCCACLRQSTRESVHYTSSAQGGASTRIMLPENGHPLMDSTL
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| BDBM50195700 |
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| n/a |
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| Name | BDBM50195700 |
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| Synonyms: | CHEMBL3975893 |
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| Type | Small organic molecule |
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| Emp. Form. | C33H32ClNO6 |
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| Mol. Mass. | 574.063 |
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| SMILES | COc1cc(cc(OC)c1C)C(=O)N(CCCc1ccccc1)Cc1ccc(Oc2ccc(Cl)cc2C(O)=O)cc1 |
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| Structure | 
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