| Reaction Details |
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 | Report a problem with these data |
| Target | Integrin beta-8 |
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| Ligand | BDBM50199197 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1621501 (CHEMBL3863784) |
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| IC50 | >10000±n/a nM |
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| Citation |  Reed, NI; Tang, YZ; McIntosh, J; Wu, Y; Molnar, KS; Civitavecchia, A; Sheppard, D; DeGrado, WF; Jo, H Exploring ACS Med Chem Lett7:902-907 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Integrin beta-8 |
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| Name: | Integrin beta-8 |
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| Synonyms: | ITB8_HUMAN | ITGB8 |
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| Type: | Protein |
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| Mol. Mass.: | 85643.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 769 |
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| Sequence: | MCGSALAFFTAAFVCLQNDRRGPASFLWAAWVFSLVLGLGQGEDNRCASSNAASCARCLA
LGPECGWCVQEDFISGGSRSERCDIVSNLISKGCSVDSIEYPSVHVIIPTENEINTQVTP
GEVSIQLRPGAEANFMLKVHPLKKYPVDLYYLVDVSASMHNNIEKLNSVGNDLSRKMAFF
SRDFRLGFGSYVDKTVSPYISIHPERIHNQCSDYNLDCMPPHGYIHVLSLTENITEFEKA
VHRQKISGNIDTPEGGFDAMLQAAVCESHIGWRKEAKRLLLVMTDQTSHLALDSKLAGIV
VPNDGNCHLKNNVYVKSTTMEHPSLGQLSEKLIDNNINVIFAVQGKQFHWYKDLLPLLPG
TIAGEIESKAANLNNLVVEAYQKLISEVKVQVENQVQGIYFNITAICPDGSRKPGMEGCR
NVTSNDEVLFNVTVTMKKCDVTGGKNYAIIKPIGFNETAKIHIHRNCSCQCEDNRGPKGK
CVDETFLDSKCFQCDENKCHFDEDQFSSESCKSHKDQPVCSGRGVCVCGKCSCHKIKLGK
VYGKYCEKDDFSCPYHHGNLCAGHGECEAGRCQCFSGWEGDRCQCPSAAAQHCVNSKGQV
CSGRGTCVCGRCECTDPRSIGRFCEHCPTCYTACKENWNCMQCLHPHNLSQAILDQCKTS
CALMEQQHYVDQTSECFSSPSYLRIFFIIFIVTFLIGLLKVLIIRQVILQWNSNKIKSSS
DYRVSASKKDKLILQSVCTRAVTYRREKPEEIKMDISKLNAHETFRCNF
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| BDBM50199197 |
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| n/a |
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| Name | BDBM50199197 |
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| Synonyms: | CHEMBL3923968 | US10131658, Compound 11 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H36N6O6S |
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| Mol. Mass. | 584.687 |
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| SMILES | OC(=O)[C@H](Cc1ccc(NC(=O)CCCCNC2=NCCN2)cc1)NC(=O)[C@@H]1CCCN1S(=O)(=O)c1ccccc1 |r,t:17| |
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| Structure | 
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