| Reaction Details |
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 | Report a problem with these data |
| Target | Proteinase-activated receptor 2 |
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| Ligand | BDBM50203290 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1624982 (CHEMBL3867394) |
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| EC50 | 700±n/a nM |
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| Citation |  Yau, MK; Liu, L; Suen, JY; Lim, J; Lohman, RJ; Jiang, Y; Cotterell, AJ; Barry, GD; Mak, JY; Vesey, DA; Reid, RC; Fairlie, DP PAR2 Modulators Derived from GB88. ACS Med Chem Lett7:1179-1184 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Proteinase-activated receptor 2 |
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| Name: | Proteinase-activated receptor 2 |
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| Synonyms: | F2RL1 | GPR11 | PAR2 | PAR2_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44152.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1497756 |
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| Residue: | 397 |
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| Sequence: | MRSPSAAWLLGAAILLAASLSCSGTIQGTNRSSKGRSLIGKVDGTSHVTGKGVTVETVFS
VDEFSASVLTGKLTTVFLPIVYTIVFVVGLPSNGMALWVFLFRTKKKHPAVIYMANLALA
DLLSVIWFPLKIAYHIHGNNWIYGEALCNVLIGFFYGNMYCSILFMTCLSVQRYWVIVNP
MGHSRKKANIAIGISLAIWLLILLVTIPLYVVKQTIFIPALNITTCHDVLPEQLLVGDMF
NYFLSLAIGVFLFPAFLTASAYVLMIRMLRSSAMDENSEKKRKRAIKLIVTVLAMYLICF
TPSNLLLVVHYFLIKSQGQSHVYALYIVALCLSTLNSCIDPFVYYFVSHDFRDHAKNALL
CRSVRTVKQMQVSLTSKKHSRKSSSYSSSSTTVKTSY
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| BDBM50203290 |
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| n/a |
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| Name | BDBM50203290 |
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| Synonyms: | CHEMBL3896632 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H42N4O6 |
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| Mol. Mass. | 578.6991 |
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| SMILES | CC[C@H](C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)c1ccno1)C(=O)N1CCC2(CC1)CC(=O)c1ccccc1O2 |r| |
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| Structure | 
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