| Reaction Details |
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 | Report a problem with these data |
| Target | Free fatty acid receptor 4 |
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| Ligand | BDBM50203667 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1625791 (CHEMBL3868260) |
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| EC50 | 34±n/a nM |
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| Citation |  Lombardo, M; Bender, K; London, C; Plotkin, MA; Kirkland, M; Mane, J; Pachanski, M; Geissler, W; Cummings, J; Habulihaz, B; Akiyama, TE; Di Salvo, J; Madeira, M; Pols, J; Powles, MA; Finley, MF; Johnson, E; Roussel, T; Uebele, VN; Crespo, A; Leung, D; Alleyne, C; Trusca, D; Lei, Y; Howard, AD; Ujjainwalla, F; Tata, JR; Sinz, CJ Discovery of benzofuran propanoic acid GPR120 agonists: From uHTS hit to mechanism-based pharmacodynamic effects. Bioorg Med Chem Lett26:5724-5728 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Free fatty acid receptor 4 |
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| Name: | Free fatty acid receptor 4 |
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| Synonyms: | FFAR4_MOUSE | Ffar4 | Free fatty acid receptor 4 | G-protein coupled receptor GT01 | Gpr120 | O3far1 | Omega-3 fatty acid receptor 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40828.60 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1454435 |
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| Residue: | 361 |
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| Sequence: | MSPECAQTTGPGPSHTLDQVNRTHFPFFSDVKGDHRLVLSVVETTVLGLIFVVSLLGNVC
ALVLVARRRRRGATASLVLNLFCADLLFTSAIPLVLVVRWTEAWLLGPVVCHLLFYVMTM
SGSVTILTLAAVSLERMVCIVRLRRGLSGPGRRTQAALLAFIWGYSALAALPLCILFRVV
PQRLPGGDQEIPICTLDWPNRIGEISWDVFFVTLNFLVPGLVIVISYSKILQITKASRKR
LTLSLAYSESHQIRVSQQDYRLFRTLFLLMVSFFIMWSPIIITILLILIQNFRQDLVIWP
SLFFWVVAFTFANSALNPILYNMSLFRNEWRKIFCCFFFPEKGAIFTDTSVRRNDLSVIS
S
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| BDBM50203667 |
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| n/a |
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| Name | BDBM50203667 |
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| Synonyms: | CHEMBL3961950 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H18ClFO4 |
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| Mol. Mass. | 400.827 |
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| SMILES | OC(=O)CCCOc1ccc(cc1)-c1cc(Oc2cccc(F)c2)ccc1Cl |
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| Structure | 
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