| Reaction Details |
|---|
 | Report a problem with these data |
| Target | cAMP-specific 3',5'-cyclic phosphodiesterase 4C |
|---|
| Ligand | BDBM50221007 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_157378 (CHEMBL763643) |
|---|
| Ki | 2.7±n/a nM |
|---|
| Citation |  Kim, E; Chun, HO; Jung, SH; Kim, JH; Lee, JM; Suh, BC; Xiang, MX; Rhee, CK Improvement of therapeutic index of phosphodiesterase type IV inhibitors as anti-Asthmatics. Bioorg Med Chem Lett13:2355-8 (2003) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4C |
|---|
| Name: | cAMP-specific 3',5'-cyclic phosphodiesterase 4C |
|---|
| Synonyms: | Dpde1 | PDE4C_RAT | Pde4c |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 60038.21 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_104732 |
|---|
| Residue: | 536 |
|---|
| Sequence: | NSSRTSSAASDLHGEDMIVTPFAQVLASLRTVRSNVAALAHGAGSATRQALLGTPPQSSQ
QAAPAEESGLQLAQETLEELDWCLEQLETLQTRRSVGEMASNKFKRMLNRELTHLSETSR
SGNQVSEYISQTFLDQQAEVELPAPPTEDHPWPMAQITGLRKSCHTSLPTAAIPRFGVQT
DQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAVIFRVLQERDLLKTFQIPADTLLRYL
LTLEGHYHSNVAYHNSIHAADVVQSAHVLLGTPALEAVFTDLEVLAAIFACAIHDVDHPG
VSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQGENCDIFQNLSTKQKLSLRRMVID
MVLATDMSKHMSLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPAKPL
PLYRQWTERIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWAD
LVHPDAQELLDTLEDNREWYQSRVPCSPPHAIGPDRFKFELTLEETEEEEEEDERH
|
|
|
|---|
| BDBM50221007 |
|---|
| n/a |
|---|
| Name | BDBM50221007 |
|---|
| Synonyms: | CHEMBL80258 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H22N2O3 |
|---|
| Mol. Mass. | 290.3575 |
|---|
| SMILES | CCC(=O)N\N=C\c1ccc(OC)c(OC2CCCC2)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
